Li Xumao, Xie Yuhui, Chen Xiangyu, Cui Xidong, Sun Guangbin
Department of Otorhinolaryngology-Head and Neck Surgery,Huashan Hospital,Fudan University,Shanghai,200040,China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Oct;38(10):903-906. doi: 10.13201/j.issn.2096-7993.2024.10.004.
To retrospectively analyze the clinical effect of biomaterial combined with silicone keel technology in the prevention and treatment of vocal folds adhesion. The basic data, perioperative conditions and prognosis of 21 cases of vocal folds adhesion treated by biofilm-silicone keel complex were retrospectively analyzed in Huashan Hospital Fudan University. A total of 21 patients were enrolled in this study(19 males(90.5%), 2 females(9.5%). Among these patients, 18 cases of early glottic laryngeal carcinoma(T1b), 1 case of bilateral vocal folds leukoplecta and 2 cases of postoperative vocal folds adhesion. No accidental rupture of the silicone keel occurred during perioperative period, and the silicone keel was removed in 22.4±2.6 days. All patients were reviewed after removing the silicone keel, the overall effective rate was 90.5%(19/21). Postoperative complications occurred in 5 patients(1 laryngeal infection, 4 granulation tissue hyperplasia), all of whom were cured after conservative treatment. This study explored the feasibility of biomaterial in the treatment of vocal folds adhesion. The biomaterial-silicone keel complex technology is simple to operate and has effect on the prevention of vocal folds adhesions, which is worth of clinical promotion.
回顾性分析生物材料联合硅胶支架技术在防治声带粘连中的临床效果。对复旦大学附属华山医院采用生物膜-硅胶支架复合体治疗的21例声带粘连患者的基础资料、围手术期情况及预后进行回顾性分析。本研究共纳入21例患者(男性19例(90.5%),女性2例(9.5%)。其中,早期声门型喉癌(T1b)18例,双侧声带白斑1例,术后声带粘连2例。围手术期硅胶支架未发生意外断裂,硅胶支架于22.4±2.6天取出。取出硅胶支架后对所有患者进行复查,总有效率为90.5%(19/21)。5例患者出现术后并发症(1例喉部感染,4例肉芽组织增生),均经保守治疗治愈。本研究探讨了生物材料治疗声带粘连的可行性。生物材料-硅胶支架复合体技术操作简单,对预防声带粘连有效果,值得临床推广。