Peng Jieying, Zheng Hongliang, Li Meng, Wang Wei, Zhu Minhui, Jiang Hao, Zhang Caiyun, Gao Yingna, Chen Mengjie, Chen Shicai
Department of Otorhinolaryngology Head and Neck Surgery,the First Affiliated Hospital of Naval Medical University(Changhai Hospital),Shanghai,200433,China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Oct;38(10):917-922. doi: 10.13201/j.issn.2096-7993.2024.10.007.
To analyze the efficacy of endoscopic CO₂ laser arytenoidectomy in treating bilateral vocal cord paralysis. Ninety-five patients who underwent endoscopic CO₂ laser arytenoidectomy for bilateral vocal cord paralysis at the First Affiliated Hospital of Naval Medical University(Changhai Hospital) of Shanghai from January 2009 to December 2022 were included in this study. Among them, 59 patients underwent endoscopic CO₂ laser arytenoidectomy as their first glottic enlargement surgery(Group A), while 36 patients, who had previously undergone two unsuccessful CO₂ laser-assisted posterior cordotomies, underwent endoscopic CO₂ laser arytenoidectomy as a subsequent surgery(Group B). Swallowing function, electronic laryngoscopy, perceptual voice evaluation, and objective voice analysis indicators were statistically analyzed before and after surgery to evaluate clinical efficacy. The extubation rate after the first surgery was 84.75% in Group A and 86.11% in Group B, with total extubation rates of 94.92% and 94.44%, respectively. There were no significant differences between the two groups in preoperative and postoperative swallowing function, glottic size, or various voice evaluation indicators(>0.05). Within-group comparisons showed that postoperative swallowing function, glottic closure during phonation, perceptual evaluations of G(grade of hoarseness), A(asthenia), and B(breathiness) significantly worsened, with increased grades. The maximum transverse diameter of the posterior glottis during inspiration significantly increased, and the VHI-10 score was significantly higher postoperatively. Jitter, shimmer, and the harmonics-to-noise ratio significantly deteriorated, and maximum phonation time significantly shortened(<0.05). No significant differences were observed in postoperative R(roughness) and S(strain) compared to preoperative values(>0.05). Endoscopic CO₂ laser arytenoidectomy can impair voice quality to some extent but effectively alleviates breathing difficulties in patients with bilateral vocal cord paralysis. For patients who did not achieve successful extubation with CO₂ laser-assisted posterior cordotomy, endoscopic CO₂laser arytenoidectomy is an effective reoperative method, ensuring a high extubation rate while preserving certain voice functions.
分析内镜下二氧化碳激光杓状软骨切除术治疗双侧声带麻痹的疗效。纳入2009年1月至2022年12月在上海海军军医大学第一附属医院(长海医院)接受内镜下二氧化碳激光杓状软骨切除术治疗双侧声带麻痹的95例患者。其中,59例患者首次接受内镜下二氧化碳激光杓状软骨切除术作为声门扩大手术(A组),36例患者此前接受过两次二氧化碳激光辅助后索切开术均未成功,随后接受内镜下二氧化碳激光杓状软骨切除术(B组)。对手术前后的吞咽功能、电子喉镜检查、嗓音感知评估和客观嗓音分析指标进行统计学分析,以评估临床疗效。A组首次手术后拔管率为84.75%,B组为86.11%,总拔管率分别为94.92%和94.44%。两组术前和术后吞咽功能、声门大小或各项嗓音评估指标之间无显著差异(>0.05)。组内比较显示,术后吞咽功能、发声时声门闭合、G(嘶哑程度)、A(无力)和B(气息声)的感知评估显著恶化,分级增加。吸气时后声门最大横径显著增加,术后VHI-10评分显著升高。抖动、闪烁和谐波噪声比显著恶化,最大发声时间显著缩短(<0.05)。术后R(粗糙度)和S(紧张度)与术前值相比无显著差异(>0.05)。内镜下二氧化碳激光杓状软骨切除术虽会在一定程度上损害嗓音质量,但能有效缓解双侧声带麻痹患者的呼吸困难。对于二氧化碳激光辅助后索切开术未能成功拔管的患者,内镜下二氧化碳激光杓状软骨切除术是一种有效的再次手术方法,可确保高拔管率,同时保留一定的嗓音功能。