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亚甲蓝注入法:资源有限环境下诊断胸膜腹膜瘘的一种经济有效的方法。

Methylene Blue Instillation: A Cost-Effective Diagnostic Approach for Pleuroperitoneal Fistula in Resource-Limited Settings.

作者信息

García Romero José Manuel, Guerrero Morales Pedro Hugo, Alegria Arias Ana Laura, de Noriega Guzmán Daniela, Bulle Parra Mariana

机构信息

Transplant and Donation Department, Regional General Hospital 1 of the Mexican Social Security Institute, Querétaro, MEX.

General Practice, Health Clinic 56 Amealco of the Mexican Social Security Institute, Querétaro, MEX.

出版信息

Cureus. 2024 Sep 9;16(9):e69034. doi: 10.7759/cureus.69034. eCollection 2024 Sep.

DOI:10.7759/cureus.69034
PMID:39391407
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11464615/
Abstract

A pleuroperitoneal fistula, an uncommon complication of peritoneal dialysis, involves a connection between the peritoneal cavity and the pleural space. This case highlights a cost-effective diagnostic option for detecting these fistulas in primary care hospitals and emphasizes the importance of considering this condition in patients with a history of peritoneal dialysis and persistent pleural effusion. We present a case of a 55-year-old female patient undergoing peritoneal dialysis for end-stage renal disease who developed a pleuroperitoneal fistula, leading to persistent pleural effusion. This condition was successfully diagnosed using methylene blue instillation into the dialysis bags, demonstrating a potentially viable diagnostic technique that is effective, safe, and cost-efficient for primary and secondary care hospitals. The presented case underscores that pleural effusion, as a complication with high mortality, should be considered in any patient with end-stage renal disease presenting with dyspnea, desaturation, and pleuritic pain secondary to peritoneal dialysis sessions. Furthermore, the use of methylene blue is proposed as a cost-effective and accessible diagnostic alternative. This approach not only facilitates accurate diagnosis but also simplifies the diagnostic process without relying on advanced imaging technologies that might not be available.

摘要

胸膜腹膜瘘是腹膜透析的一种罕见并发症,它涉及腹膜腔与胸膜腔之间的连通。本病例突出了在基层医院检测这些瘘管的一种经济有效的诊断方法,并强调了在有腹膜透析病史且持续存在胸腔积液的患者中考虑这种情况的重要性。我们报告一例55岁女性患者,因终末期肾病接受腹膜透析,发生了胸膜腹膜瘘,导致持续性胸腔积液。通过向透析袋中注入亚甲蓝成功诊断了这种情况,这表明对于基层和二级医疗机构而言,这是一种有效、安全且经济高效的潜在可行诊断技术。该病例强调,对于任何因腹膜透析出现呼吸困难、低氧血症和胸膜炎性疼痛的终末期肾病患者,都应考虑胸腔积液这种具有高死亡率的并发症。此外,建议使用亚甲蓝作为一种经济有效且易于获得的诊断选择。这种方法不仅有助于准确诊断,还简化了诊断过程,无需依赖可能无法获得的先进成像技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/218e/11464615/137197339790/cureus-0016-00000069034-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/218e/11464615/c56b39e654d5/cureus-0016-00000069034-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/218e/11464615/e9921adde2e0/cureus-0016-00000069034-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/218e/11464615/cf90b2207432/cureus-0016-00000069034-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/218e/11464615/137197339790/cureus-0016-00000069034-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/218e/11464615/c56b39e654d5/cureus-0016-00000069034-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/218e/11464615/e9921adde2e0/cureus-0016-00000069034-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/218e/11464615/cf90b2207432/cureus-0016-00000069034-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/218e/11464615/137197339790/cureus-0016-00000069034-i04.jpg

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本文引用的文献

1
Embryological, anatomical and clinical considerations on pleuroperitoneal communication.关于胸膜腹膜交通的胚胎学、解剖学及临床考量
Pleura Peritoneum. 2023 Jun 19;8(3):101-111. doi: 10.1515/pp-2023-0013. eCollection 2023 Sep.
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Thoracoscopic mesh implantation as a definitive treatment approach for peritoneal dialysis-associated hydrothorax.胸腔镜下网片植入术作为治疗腹膜透析相关性胸腔积液的一种确定性方法。
Updates Surg. 2022 Dec;74(6):2011-2017. doi: 10.1007/s13304-022-01356-9. Epub 2022 Aug 21.
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The new method to make diagnosis and identify the location of leakage of pleuroperitoneal communication in peritoneal dialysis patients.
一种新方法,用于诊断和确定腹膜透析患者胸腹漏的位置。
CEN Case Rep. 2022 Nov;11(4):471-476. doi: 10.1007/s13730-022-00701-6. Epub 2022 Apr 15.
4
Modalities of Diagnosis and Management of Peritoneal Dialysis-related Hydrothorax Including Videothoracoscopy-assisted Repair: A Single-center Experience.包括电视胸腔镜辅助修复在内的腹膜透析相关胸腔积液的诊断和管理方式:单中心经验
Indian J Nephrol. 2021 Nov-Dec;31(6):574-579. doi: 10.4103/ijn.IJN_101_20. Epub 2021 Nov 13.
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Surgical management of pleuro-peritoneal fistula in chronic renal failure patient-safety and effectiveness.慢性肾衰竭患者胸膜腹膜瘘的外科治疗——安全性与有效性
J Thorac Dis. 2021 May;13(5):2979-2985. doi: 10.21037/jtd-20-3327.
6
A case of pleuroperitoneal communication in which establishing a laparoscopic pneumoperitoneum was useful for the detection of a fistula.一例胸膜腹膜相通病例,其中建立腹腔镜气腹术有助于瘘管的检测。
Surg Case Rep. 2021 Mar 5;7(1):64. doi: 10.1186/s40792-021-01147-1.
7
The Use of Pleural Fluid to Serum Glucose Ratio in Establishing the Diagnosis of a Not So Sweet PD-Related Hydrothorax: Case Report and Literature Review.利用胸水与血清葡萄糖比值诊断非典型的帕金森病相关胸腔积液:病例报告及文献综述
Case Rep Nephrol. 2020 Sep 7;2020:8811288. doi: 10.1155/2020/8811288. eCollection 2020.
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The effectiveness and safety of computed tomographic peritoneography and video-assisted thoracic surgery for hydrothorax in peritoneal dialysis patients: A retrospective cohort study in Japan.计算机断层扫描腹膜造影术和电视辅助胸腔镜手术治疗腹膜透析患者胸腔积液的效果和安全性:日本的一项回顾性队列研究。
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