Nwanguma Adaugo, Arora Kshitij
Pathology and Translational Pathobiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Cureus. 2024 Sep 10;16(9):e69062. doi: 10.7759/cureus.69062. eCollection 2024 Sep.
Actinomyces can cause severe infections in the gynecological tract, such as pelvic inflammatory disease (PID) and tubo-ovarian abscess. It's essential to accurately diagnose actinomycotic granules (AMGs) in gynecological specimens to ensure proper treatment, significantly differentiating them from pseudoactinomycotic radiate granules (PAMRAGs), a non-pathologic condition. This article describes a case of a 61-year-old postmenopausal woman with an intrauterine device (IUD) who was diagnosed with PAMRAGs in an endometrial biopsy specimen. This case highlights the challenges in diagnosis, emphasizing the need to understand the distinguishing features and staining properties of PAMRAGs and AMGs to avoid diagnostic errors and awareness of the histological distinguishing features and staining properties of PAMRAGs and AMGs to avert diagnostic mistakes.
放线菌可引起生殖道严重感染,如盆腔炎(PID)和输卵管卵巢脓肿。准确诊断妇科标本中的放线菌颗粒(AMG)对于确保恰当治疗至关重要,要将其与非病理性的假放线菌放射状颗粒(PAMRAG)显著区分开来。本文描述了一例61岁绝经后带宫内节育器(IUD)的女性,其子宫内膜活检标本中被诊断为PAMRAG。该病例凸显了诊断中的挑战,强调需要了解PAMRAG和AMG的鉴别特征及染色特性,以避免诊断错误,同时要知晓PAMRAG和AMG的组织学鉴别特征及染色特性以防止诊断失误。