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肾切除术后11年出现同时性胃和胰腺多发转移的肾细胞癌切除病例

A Resected Case of Simultaneous Gastric and Multiple Pancreatic Metastases of Renal Cell Carcinoma 11 Years After Nephrectomy.

作者信息

Mori Hideki, Sunagawa Hiroki, Matsumoto Hirofumi

机构信息

Department of Gastroenterology, Nakagami Hospital, Okinawa, JPN.

Department of Surgery, Nakagami Hospital, Okinawa, JPN.

出版信息

Cureus. 2024 Sep 10;16(9):e69108. doi: 10.7759/cureus.69108. eCollection 2024 Sep.

DOI:10.7759/cureus.69108
PMID:39391452
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11465953/
Abstract

A 50-year-old man with a history of nephrectomy for renal cell carcinoma (RCC) 11 years prior was diagnosed with gastric and multiple pancreatic metastases of RCC. He underwent a pyloric gastrectomy and total pancreatic resection. RCC metastases to the pancreas are rare, and gastric metastases are even rarer. This case represents a rare instance of simultaneous RCC metastases to both the stomach and pancreas. Although there is no difference in prognosis between solitary and multiple pancreatic metastases, surgical resection is recommended even for multiple lesions. However, preoperative imaging often fails to identify all pancreatic metastatic lesions, making total pancreatectomy a consideration for ensuring complete resection, especially when preoperative detection is challenging.

摘要

一名50岁男性,11年前因肾细胞癌(RCC)接受了肾切除术,现被诊断为RCC胃和胰腺多发转移。他接受了幽门胃切除术和全胰切除术。RCC转移至胰腺罕见,转移至胃则更为罕见。该病例是RCC同时转移至胃和胰腺的罕见情况。尽管孤立性和多发性胰腺转移的预后无差异,但即使是多发病变也建议手术切除。然而,术前影像学检查往往无法识别所有胰腺转移病灶,这使得全胰切除术成为确保完整切除的一种选择,尤其是在术前检测具有挑战性时。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c03/11465953/88c20a18fd6b/cureus-0016-00000069108-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c03/11465953/39e9897dfa50/cureus-0016-00000069108-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c03/11465953/b90e980e165e/cureus-0016-00000069108-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c03/11465953/29704a299493/cureus-0016-00000069108-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c03/11465953/88c20a18fd6b/cureus-0016-00000069108-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c03/11465953/39e9897dfa50/cureus-0016-00000069108-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c03/11465953/b90e980e165e/cureus-0016-00000069108-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c03/11465953/29704a299493/cureus-0016-00000069108-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c03/11465953/88c20a18fd6b/cureus-0016-00000069108-i04.jpg

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本文引用的文献

1
Surgical-only treatment of pancreatic and extra-pancreatic metastases from renal cell carcinoma - quality of life and survival analysis.肾细胞癌胰腺及胰腺外转移灶的单纯手术治疗——生活质量与生存分析
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Surgical resection does not improve survival in patients with renal metastases to the pancreas in the era of tyrosine kinase inhibitors.在酪氨酸激酶抑制剂时代,手术切除并不能提高胰腺肾转移患者的生存率。
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Pancreatic metastasis from renal cell carcinoma: which patients benefit from surgical resection?肾细胞癌的胰腺转移:哪些患者能从手术切除中获益?
Ann Surg Oncol. 2008 Apr;15(4):1161-8. doi: 10.1245/s10434-007-9782-0. Epub 2008 Jan 15.