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Phase 3 trial of everolimus for metastatic renal cell carcinoma : final results and analysis of prognostic factors.依维莫司治疗转移性肾细胞癌的 3 期临床试验：最终结果和预后因素分析。
Cancer. 2010 Sep 15;116(18):4256-65. doi: 10.1002/cncr.25219.
2
Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): final analysis of overall survival.贝伐珠单抗联合干扰素 α-2a 治疗转移性肾细胞癌的 III 期临床试验（AVOREN）：总生存的最终分析。
J Clin Oncol. 2010 May 1;28(13):2144-50. doi: 10.1200/JCO.2009.26.7849. Epub 2010 Apr 5.
3
Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial.帕唑帕尼治疗局部晚期或转移性肾细胞癌：一项随机 III 期试验结果。
J Clin Oncol. 2010 Feb 20;28(6):1061-8. doi: 10.1200/JCO.2009.23.9764. Epub 2010 Jan 25.
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Quality of life in patients with metastatic renal cell carcinoma: the importance of patient-reported outcomes.转移性肾细胞癌患者的生活质量：患者报告结局的重要性。
Cancer Treat Rev. 2009 Dec;35(8):733-7. doi: 10.1016/j.ctrv.2009.07.003. Epub 2009 Aug 21.
5
Toxicity associated with the long-term use of targeted therapies in patients with advanced renal cell carcinoma.晚期肾细胞癌患者长期使用靶向治疗相关的毒性。
Expert Rev Anticancer Ther. 2009 Jun;9(6):795-805. doi: 10.1586/era.09.29.
6
Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma.舒尼替尼与干扰素α治疗转移性肾细胞癌患者的总生存期及更新结果比较
J Clin Oncol. 2009 Aug 1;27(22):3584-90. doi: 10.1200/JCO.2008.20.1293. Epub 2009 Jun 1.
7
Renal cell carcinoma: ESMO clinical recommendations for diagnosis, treatment and follow-up.肾细胞癌：ESMO关于诊断、治疗及随访的临床建议
Ann Oncol. 2009 May;20 Suppl 4:81-2. doi: 10.1093/annonc/mdp137.
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Sorafenib for treatment of renal cell carcinoma: Final efficacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial.索拉非尼治疗肾细胞癌：肾癌全球评估试验中III期治疗方案的最终疗效和安全性结果
J Clin Oncol. 2009 Jul 10;27(20):3312-8. doi: 10.1200/JCO.2008.19.5511. Epub 2009 May 18.
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EORTC-GU group expert opinion on metastatic renal cell cancer.欧洲癌症研究与治疗组织泌尿生殖系统肿瘤组关于转移性肾细胞癌的专家意见
Eur J Cancer. 2009 Mar;45(5):765-73. doi: 10.1016/j.ejca.2008.12.010. Epub 2009 Jan 20.
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Cancer-specific survival outcomes among patients treated during the cytokine era of kidney cancer (1989-2005): a benchmark for emerging targeted cancer therapies.肾癌细胞因子治疗时代（1989 - 2005年）接受治疗患者的癌症特异性生存结果：新兴靶向癌症治疗的基准。
Cancer. 2008 Nov 1;113(9):2457-63. doi: 10.1002/cncr.23851.

转移性肾细胞癌治疗的新视角：引言和历史概述。

New perspectives on the treatment of metastatic renal cell carcinoma: an introduction and historical overview.

机构信息

Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA.

出版信息

Oncologist. 2011;16 Suppl 2(Suppl 2):1-3. doi: 10.1634/theoncologist.2011-S2-01.

DOI:10.1634/theoncologist.2011-S2-01
PMID:21346034
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3868198/
Abstract

The content of the supplement is summarized, including a review of the pathogenesis and diagnosis of renal cell carcinoma and the efficacy and safety of the currently available targeted therapies.

摘要

该补充剂的内容概述，包括肾细胞癌的发病机制和诊断的回顾，以及目前可用的靶向治疗的疗效和安全性。