中国老年人家用化学品使用与认知功能的关联

Association of household chemicals use with cognitive function among Chinese older adults.

作者信息

Wang Yanrong, Zhu Yongbin, Wu Yueping, Shi Liping, Yang Yue, Liu Xiaojuan, Li Jiangping

机构信息

Department of Epidemiology and Health Statistics, School of Public Health, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, 750004, China.

Key Laboratory of Environmental Factors and Chronic Disease Control, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, 750004, China.

出版信息

Heliyon. 2024 Sep 13;10(19):e37765. doi: 10.1016/j.heliyon.2024.e37765. eCollection 2024 Oct 15.

DOI:10.1016/j.heliyon.2024.e37765

PMID:39391473

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11466578/

Abstract

BACKGROUND

The paucity of empirical evidence supporting a correlation between the utilization of household chemicals and cognitive decline in Chinese older adults.

METHODS

The data utilized for this study originated from the Chinese Longitudinal Healthy Longevity Survey (CLHLS 2018). Using regression models to investigate the relationship between exposure to household chemicals and cognitive decline, and evaluate the impact of different fields on cognitive function.

RESULTS

The use of household chemicals was associated with a decline in cognitive function (anti-caries agent, OR = 1.68, P = 0.040; air freshener, OR = 2.48, P = 0.002; disinfectant, OR = 1.40, P = 0.033). The more frequent the use of household chemicals, the worse the cognitive function (Model1: OR = 2.54, P = 0.024; Model2: OR = 3.23, P = 0.006; Model3: OR = 3.59, P = 0.003).

CONCLUSION

The study has uncovered a correlation between the utilization of household chemicals and cognitive decline in individuals aged 65 years and over in China.

摘要

背景

支持中国老年人使用家用化学品与认知能力下降之间存在关联的实证证据匮乏。

方法

本研究使用的数据源自中国健康与养老追踪调查（CLHLS 2018）。采用回归模型研究接触家用化学品与认知能力下降之间的关系，并评估不同领域对认知功能的影响。

结果

使用家用化学品与认知功能下降有关（防龋剂，OR = 1.68，P = 0.040；空气清新剂，OR = 2.48，P = 0.002；消毒剂，OR = 1.40，P = 0.033）。家用化学品使用频率越高，认知功能越差（模型1：OR = 2.54，P = 0.024；模型2：OR = 3.23，P = 0.006；模型3：OR = 3.59，P = 0.003）。