The pH-sensing GPR68 and Rap1A: new kids in the arterial remodeling block.
作者信息
Taylor Jade L, Daghbouche-Rubio Nuria, Martín-Aragón Baudel Miguel
机构信息
Department of Pharmacology, University of California, Davis, California, United States.
出版信息
Am J Physiol Heart Circ Physiol. 2024 Nov 1;327(5):H1208-H1209. doi: 10.1152/ajpheart.00671.2024. Epub 2024 Oct 11.
Abstract
摘要
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The Effects of Acidosis on eNOS in the Systemic Vasculature: A Focus on Early Postnatal Ontogenesis.酸中毒对全身血管中 eNOS 的影响：聚焦于早期产后发育。
Int J Mol Sci. 2022 May 26;23(11):5987. doi: 10.3390/ijms23115987.
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Distinct Signaling Functions of Rap1 Isoforms in NO Release From Endothelium.Rap1亚型在内皮细胞一氧化氮释放中的不同信号功能
Front Cell Dev Biol. 2021 Jun 17;9:687598. doi: 10.3389/fcell.2021.687598. eCollection 2021.
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Acidification of the intimal fluid: the perfect storm for atherogenesis.内膜液酸化：动脉粥样硬化形成的完美风暴。
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Extracellular acidosis contracts coronary but neither renal nor mesenteric artery via modulation of H+,K+-ATPase, voltage-gated K+ channels and L-type Ca2+ channels.细胞外酸中毒通过调节H⁺，K⁺-ATP酶、电压门控钾通道和L型钙通道使冠状动脉收缩，但不影响肾动脉和肠系膜动脉。
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