用于多环苯并氮杂卓组装的N-杂环卡宾催化：区域选择性分子内串联自由基环化
N-Heterocyclic Carbene Catalysis for Polycyclic Benzazepines Assembly: Regioselective Intramolecular Tandem Radical Cyclization.
作者信息
Feng Zhiming, Wu Lili, Zhou Cong-Ying, Wang Chengming
机构信息
College of Chemistry and Materials Science, Jinan University, Guangzhou, Guangdong 511443, China.
出版信息
Org Lett. 2024 Oct 25;26(42):9068-9072. doi: 10.1021/acs.orglett.4c03303. Epub 2024 Oct 11.
PMID:39392687
Abstract
A variety of polycyclic benzazepines were rapidly constructed by NHC-catalyzed regioselective redox-neutral intramolecular tandem cyclization. Initial mechanistic studies revealed that a SET radical process was possibly involved.
摘要
通过NHC催化的区域选择性氧化还原中性分子内串联环化反应，快速构建了多种多环苯并氮杂卓。初步机理研究表明，可能涉及单电子转移自由基过程。
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