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1型糖尿病初显期成年人的心理韧性与糖化血红蛋白及关键社会心理因素的关联

The association of resilience with HbA1c and key psychosocial factors in emerging adults with type 1 diabetes.

作者信息

O'Daffer Alison, Yi-Frazier Joyce P, Roberts Alissa J, Lowry Sarah J, Pihoker Catherine, Hirsch Irl B, Weaver Kathryn W, Zenno Anna, Malik Faisal S

机构信息

Joint Doctoral Program of Clinical Psychology, San Diego State University/University of California, San Diego, CA, United States.

Department of Psychiatry, University of California, San Diego, La Jolla, CA, United States.

出版信息

J Pediatr Psychol. 2024 Dec 1;49(12):866-873. doi: 10.1093/jpepsy/jsae085.

Abstract

OBJECTIVE

Emerging adults (EAs) with type 1 diabetes (T1D) have difficulty meeting glycemic targets and have a high prevalence of mental health comorbidities. Resilience, the ability to harness resources needed to sustain one's emotional and physical well-being, may be a key factor impacting poor mental health and glycemic outcomes. We aimed to (a) evaluate the association between resilience, HbA1c, and key psychosocial factors and (b) explore whether resilience moderates the relationship between psychosocial factors (depression, diabetes-related distress, anxiety) and HbA1c in EAs with T1D.

METHOD

EAs with T1D (N = 233) (mean age = 19.9 years (SD = 1.6), range 16.8-24.7) seen at an EA-specific diabetes clinic completed resilience, diabetes-related distress, depression, and anxiety measures and had their HbA1c level evaluated. We used linear regression models and conducted moderation analyses for the resilience factor.

RESULTS

Resilience was strongly associated with HbA1c, depression, diabetes-related distress, and anxiety in EAs with T1D. We did not find evidence that resilience moderates the relationship between depression, anxiety, or diabetes-related distress and HbA1c.

CONCLUSIONS

This study found that resilience is a highly relevant psychological factor associated with HbA1c and a key mental health factor for EAs with T1D. Novel interventions are needed to ameliorate high diabetes-related distress and HbA1c, and bolstering resilience may be one avenue to explore. Future research on resilience should longitudinally characterize and evaluate whether resilience may be a mechanism underlying the relationship between poor psychosocial outcomes and not meeting glycemic targets in EAs with T1D.

摘要

目的

患有1型糖尿病(T1D)的青年期成年人(EAs)在实现血糖目标方面存在困难,且心理健康合并症的患病率很高。心理韧性,即利用维持自身情绪和身体健康所需资源的能力,可能是影响心理健康不佳和血糖结果的关键因素。我们旨在(a)评估心理韧性、糖化血红蛋白(HbA1c)与关键心理社会因素之间的关联,以及(b)探讨心理韧性是否调节了患有T1D的EAs中心理社会因素(抑郁、糖尿病相关困扰、焦虑)与HbA1c之间的关系。

方法

在一家专门针对EAs的糖尿病诊所就诊的患有T1D的EAs(N = 233)(平均年龄 = 19.9岁(标准差 = 1.6),范围16.8 - 24.7)完成了心理韧性、糖尿病相关困扰、抑郁和焦虑测量,并对其HbA1c水平进行了评估。我们使用线性回归模型,并对心理韧性因素进行了调节分析。

结果

在患有T1D的EAs中,心理韧性与HbA1c、抑郁、糖尿病相关困扰和焦虑密切相关。我们没有发现证据表明心理韧性调节了抑郁、焦虑或糖尿病相关困扰与HbA1c之间的关系。

结论

本研究发现,心理韧性是与HbA1c相关的高度相关心理因素,也是患有T1D的EAs的关键心理健康因素。需要新的干预措施来改善高糖尿病相关困扰和HbA1c,增强心理韧性可能是一条值得探索的途径。未来关于心理韧性的研究应纵向描述和评估心理韧性是否可能是患有T1D的EAs中心理社会结果不佳与未达到血糖目标之间关系的潜在机制。

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