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选择性引产可能在医院层面产生负面影响。

Elective Induction of Labor May Have Negative Effects at the Hospital Level.

作者信息

Mann Sean, James Kortney Floyd

出版信息

J Obstet Gynecol Neonatal Nurs. 2025 Mar;54(2):170-175. doi: 10.1016/j.jogn.2024.09.003. Epub 2024 Oct 10.

Abstract

Labor induction increased in the United States after the publication of A Randomized Trial of Induction Versus Expectant Management (ARRIVE) in 2018. During this trial, investigators found that elective induction at 39 weeks in low-risk nulliparous women led to similar perinatal outcomes when compared to expectant management. However, other researchers have since linked rising labor induction rates to worse hospital- and population-level outcomes. It is possible that elective induction of labor has a neutral effect on patients who are induced while at the same time lessening hospital capacity to care for other maternity patients, which leads to a negative effect on patient outcomes overall. During a trial, this represents a form of negative spillover, in which an intervention indirectly harms the comparison group and leads to overestimation of intervention benefit. Although further research is needed, evidence from ARRIVE and subsequent studies provides preliminary support for this possibility.

摘要

2018年《引产与期待管理随机试验》(ARRIVE)发表后,美国的引产率有所上升。在该试验中,研究人员发现,与期待管理相比,低风险初产妇在39周时进行择期引产会导致相似的围产期结局。然而,自那以后,其他研究人员将引产率上升与更差的医院和人群水平结局联系起来。有可能择期引产对接受引产的患者具有中性影响,同时降低了医院照顾其他产妇的能力,从而总体上对患者结局产生负面影响。在一项试验中,这代表了一种负面溢出形式,即一种干预措施间接伤害了对照组,并导致对干预效益的高估。尽管还需要进一步研究,但来自ARRIVE及后续研究的证据为这种可能性提供了初步支持。

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