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含银生物聚合物涂层棉伤口敷料作为潜在伤口愈合材料的研发与评估

Development and evaluation of silver-infused Biopolymer coated cotton wound dressings as possible wound healing material.

作者信息

Tauseef Muhammad, Azam Farooq, Iqbal Yasir, Ahmad Sheraz, Ahmad Faheem, Masood Rashid, Habib Syed Rashid, Rasheed Abher, Zafar Muhammad Sohail, Salam Abdul

机构信息

School of Engineering and Technology, National Textile University, Faisalabad, Pakistan.

Department of Chemistry, University of Sialkot-51040, Pakistan.

出版信息

Heliyon. 2024 Sep 24;10(19):e38407. doi: 10.1016/j.heliyon.2024.e38407. eCollection 2024 Oct 15.

Abstract

Wound management is a critical clinical issue, with substantial economic and social implications. Traditional dressings often lead to poor healing, impacting the effective wound repair is an ongoing challenge. So, this research aimed to investigate the development of a novel medical textile auxiliary in the form of a padded cotton bandage coated with a blend of agricultural biopolymers (xanthan gum and gum arabic) containing AgNPs with an emphasis on environmental friendliness and sustainability. The samples treated with various biopolymer blend compositions that were assessed by SEM and FTIR analysis, tensile strength, antibacterial properties, and comfort attributes, including air permeability and wicking. Antibacterial tests showed no bacterial growth on the samples, with the maximum inhibition zone measuring 3.3 mm. The mechanical and comfort tests revealed that the blend with 0.5 % xanthan gum and 1 % Arabic gum achieved the highest air permeability at 500 mm/s, the sample with the highest GSM demonstrated superior tensile strength at 42 N, and the 50 GSM sample exhibited better-wicking properties, reaching up to 1.33 cm, compared to the 100 GSM samples. This research is aimed to develop biopolymer-based cotton bandages with improved air permeability, antibacterial, tensile strength, moisture-wicking.

摘要

伤口管理是一个关键的临床问题,具有重大的经济和社会影响。传统敷料常常导致愈合不佳,影响有效的伤口修复是一项持续的挑战。因此,本研究旨在研发一种新型医用纺织辅料,其形式为涂覆有含银纳米颗粒的农业生物聚合物(黄原胶和阿拉伯胶)混合物的棉质衬垫绷带,重点在于环境友好性和可持续性。用各种生物聚合物共混物组成处理的样品通过扫描电子显微镜(SEM)和傅里叶变换红外光谱(FTIR)分析、拉伸强度、抗菌性能以及包括透气性和芯吸作用在内的舒适属性进行评估。抗菌测试表明样品上无细菌生长,最大抑菌圈为3.3毫米。机械性能和舒适性测试表明,含0.5%黄原胶和1%阿拉伯胶的共混物透气性最高,为500毫米/秒,克重最高的样品拉伸强度最优,为42牛,与100克重的样品相比,50克重的样品芯吸性能更好,可达1.33厘米。本研究旨在开发具有改善的透气性、抗菌性、拉伸强度和吸湿排汗性能的基于生物聚合物的棉质绷带。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20cd/11467561/1fd2da94d2f3/ga1.jpg

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