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经皮椎体后凸成形术治疗骨质疏松性椎体压缩骨折后再发骨折的危险因素：系统评价。

Risk factors for secondary fractures to percutaneous vertebroplasty for osteoporotic vertebral compression fractures: a systematic review.

机构信息

Guangzhou Institute of Traumatic Surgery, Department of Orthopedics, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou, China.

Department of Clinical Medicine, Guizhou Medical University, Guiyang, China.

出版信息

J Orthop Surg Res. 2021 Oct 30;16(1):644. doi: 10.1186/s13018-021-02722-w.

DOI:10.1186/s13018-021-02722-w
PMID:34717682
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8556988/
Abstract

BACKGROUND

Osteoporotic vertebral compression fracture (OVCF) is one of the most common fragile fractures, and percutaneous vertebroplasty provides considerable long-term benefits. At the same time, there are many reports of postoperative complications, among which fracture after percutaneous vertebroplasty is one of the complications after vertebroplasty (PVP). Although there are many reports on the risk factors of secondary fracture after PVP at home and abroad, there is no systematic analysis on the related factors of secondary fracture after PVP.

METHODS

The databases, such as CNKI, Wan Fang Database and PubMed, were searched for documents on secondary fractures after percutaneous vertebroplasty published at home and abroad from January 2011 to March 2021. After strictly evaluating the quality of the included studies and extracting data, a meta-analysis was conducted by using Revman 5.3 software.

RESULTS

A total of 9 articles were included, involving a total of 1882 patients, 340 of them diagnosed as secondary fractures after percutaneous vertebroplasty.

CONCLUSION

The additional history of fracture, age, bone mineral density (BMD), bone cement leakage, intravertebral fracture clefts and Cobb Angle might be risk factors related to secondary fractures after percutaneous vertebroplasty for osteoporotic vertebral compression fractures. The height of vertebral anterior and body mass index (BMI) were not correlated.

摘要

背景

骨质疏松性椎体压缩骨折（OVCF）是最常见的脆性骨折之一，经皮椎体成形术（PVP）能提供显著的长期获益。同时，有许多关于术后并发症的报道，其中经皮椎体成形术后骨折是经皮椎体成形术后并发症之一（PVP）。虽然国内外有许多关于 PVP 后再次骨折的危险因素的报道，但对 PVP 后再次骨折的相关因素尚无系统分析。

方法

检索 2011 年 1 月至 2021 年 3 月国内外发表的关于经皮椎体成形术后再次骨折的文献，检索数据库包括中国知网、万方数据库和 PubMed。对纳入研究的质量进行严格评估和数据提取后，使用 Revman 5.3 软件进行荟萃分析。

结果

共纳入 9 篇文献，共涉及 1882 例患者，其中 340 例诊断为经皮椎体成形术后再次骨折。

结论

既往骨折史、年龄、骨密度（BMD）、骨水泥渗漏、椎体内骨折裂隙和 Cobb 角可能是骨质疏松性椎体压缩性骨折经皮椎体成形术后再次骨折的危险因素。椎体前缘高度和体质量指数（BMI）与再次骨折无相关性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/9aa34208c413/13018_2021_2722_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/0b068a9f4693/13018_2021_2722_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/e298a096533e/13018_2021_2722_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/daad1daa3ac6/13018_2021_2722_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/56419d55a532/13018_2021_2722_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/c81c7776ca2d/13018_2021_2722_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/d804c549067f/13018_2021_2722_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/d3039e69909e/13018_2021_2722_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/db60f642d7d4/13018_2021_2722_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/9aa34208c413/13018_2021_2722_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/0b068a9f4693/13018_2021_2722_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/e298a096533e/13018_2021_2722_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/daad1daa3ac6/13018_2021_2722_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/56419d55a532/13018_2021_2722_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/c81c7776ca2d/13018_2021_2722_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/d804c549067f/13018_2021_2722_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/d3039e69909e/13018_2021_2722_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/db60f642d7d4/13018_2021_2722_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86fe/8556988/9aa34208c413/13018_2021_2722_Fig9_HTML.jpg

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