Cubitt Catherine, Ariyaratne Sisith, Evans Scott, Vaiyapuri Sumathi, Hughes Simon, Botchu Rajesh
College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Department of Musculoskeletal Radiology, The Royal Orthopaedic Hospital, Birmingham, UK.
Int Cancer Conf J. 2024 Jun 28;13(4):401-406. doi: 10.1007/s13691-024-00698-y. eCollection 2024 Oct.
Osseous metastatic disease is commonly encountered in breast carcinoma, which typically presents as either osteolytic, osteoblastic, or mixed lesions on imaging. Osseous metastasis presenting as a multiloculated cystic lesion with fluid-fluid levels resembling that of an aneurysmal bone cyst (ABC) is sparsely described in the literature, and even less so in the case of breast carcinoma. We report an unusual case of fluid-fluid levels in a bone metastasis to the spine in a 66-year-old female with a prior history of breast carcinoma. Magnetic resonance imaging (MRI) demonstrated a cystic lesion with fluid levels resembling that of an ABC. Computed tomography (CT)-guided biopsy revealed the lesion to be a metastasis from breast carcinoma. The management of ABCs and osseous metastases differ drastically. Accurate diagnosis and distinction between these lesions is paramount as the management of metastatic disease can have a significant impact on the quality and length of life. The presentation, differential diagnoses and imaging features of this atypical case are discussed.
骨转移性疾病在乳腺癌中很常见，在影像学上通常表现为溶骨性、成骨性或混合性病变。文献中很少描述骨转移表现为具有液-液平面的多房囊性病变，类似于骨动脉瘤样囊肿（ABC），在乳腺癌病例中更是少见。我们报告了一例66岁有乳腺癌病史的女性脊柱骨转移出现液-液平面的罕见病例。磁共振成像（MRI）显示一个具有类似于ABC液平面的囊性病变。计算机断层扫描（CT）引导下活检显示该病变为乳腺癌转移。ABC和骨转移的治疗方法截然不同。准确诊断和区分这些病变至关重要，因为转移性疾病的治疗会对生活质量和寿命产生重大影响。本文讨论了该非典型病例的表现、鉴别诊断及影像学特征。
