Chandran Vigneshwaran, Periasamy Kannan, Kaman Lileswar, Gupta Kirti, Nahar Uma
Department of Radiotherapy and Oncology, PGIMER, Chandigarh, India.
Present Address: Department of Radiation Oncology, JIPMER, Puducherry, India.
Int Cancer Conf J. 2024 Aug 27;13(4):449-453. doi: 10.1007/s13691-024-00717-y. eCollection 2024 Oct.
Small intestinal metastasis is extremely rare and only 13 cases have been reported till date and almost all such patients have presented with intestinal obstruction. The 5-year overall survival for metastatic esophageal cancer is as low as 5% while the patients with small intestinal metastasis have a median survival of only 3 months (range 1-12 months) despite undergoing radical resection of the small bowel. We present a case of a male in his 50's who presented with difficulty in swallowing for 4 months. On evaluation, he was found to have squamous cell carcinoma in the mid thoracic esophagus. He underwent radical chemo-radiation up to 60 Gy in 25 fractions over 5 weeks. One week after completion of treatment he presented with ileal obstruction and omental nodules and surgical resection and evaluation of the respective ileal segment and omental biopsy revealed a metastatic squamous cell carcinoma. The patient expired 3 months post-surgery. Carcinoma esophagus with small bowel metastasis has a very grave prognosis that patients rarely survive beyond 1 year despite undergoing resection. Hence it is imperative to consider a small bowel metastasis when such patients present with clinical features of intestinal obstruction for early diagnosis and aggressive management.
小肠转移极为罕见,迄今为止仅报道过13例,几乎所有此类患者均表现为肠梗阻。转移性食管癌的5年总生存率低至5%,而小肠转移患者尽管接受了小肠根治性切除,其生存中位数仅为3个月(范围1 - 12个月)。我们报告一例50多岁男性患者,出现吞咽困难4个月。经评估,发现其胸段中段食管有鳞状细胞癌。他接受了根治性放化疗,在5周内分25次给予60 Gy剂量。治疗结束1周后,他出现回肠梗阻和网膜结节,对相应回肠段进行手术切除及评估,网膜活检显示为转移性鳞状细胞癌。患者术后3个月死亡。食管癌伴小肠转移预后极差,患者即便接受切除,也很少能存活超过1年。因此,当此类患者出现肠梗阻临床特征时,必须考虑小肠转移,以便早期诊断并积极治疗。