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老年患者蝶枕部纤维发育不良伴囊肿形成致展神经麻痹:病例报告

Sphenoclival fibrous dysplasia with cyst formation causing abducens nerve palsy in an older patient: illustrative case.

作者信息

Nakamura Masayuki, Hasegawa Hirotaka, Yasunaga Yoichi, Nakai Yudai, Umekawa Motoyuki, Saito Nobuhito

机构信息

Departments of Neurosurgery, The University of Tokyo, Bunkyo, Tokyo, Japan.

Pathology, The University of Tokyo, Bunkyo, Tokyo, Japan.

出版信息

J Neurosurg Case Lessons. 2024 Oct 14;8(16). doi: 10.3171/CASE24424.

Abstract

BACKGROUND

Fibrous dysplasia (FD) is typically asymptomatic but is known to occasionally cause neurological symptoms such as visual disturbances. However, FD-associated abducens nerve palsy is extremely rare.

OBSERVATIONS

A 76-year-old woman had a left abducens nerve palsy due to mass effect on the abducens nerve at Dorello's canal caused by FD and its associated cyst, which was resolved by resection of the cyst through an endoscopic transnasal route.

LESSONS

Although FD is generally an asymptomatic lesion occurring in younger patients, it can occasionally cause abducens nerve palsy even in older patients. In particular, cystic degeneration within FD tends to trigger a mass effect and thus can require surgical decompression. https://thejns.org/doi/10.3171/CASE24424.

摘要

背景

骨纤维异常增殖症(FD)通常无症状,但已知偶尔会引起神经症状,如视觉障碍。然而,FD相关的展神经麻痹极为罕见。

观察结果

一名76岁女性因FD及其相关囊肿对Dorello管内展神经的占位效应而出现左侧展神经麻痹,通过鼻内镜经鼻切除囊肿后症状缓解。

经验教训

尽管FD通常是发生在年轻患者中的无症状病变,但即使在老年患者中也可能偶尔导致展神经麻痹。特别是,FD内的囊性变倾向于引发占位效应,因此可能需要手术减压。https://thejns.org/doi/10.3171/CASE24424

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23a5/11488379/bb9b14ba8407/CASE24424_figure_1.jpg

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本文引用的文献

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Haemorrhagic cystic sino-nasal fibrous dysplasia.出血性囊性鼻窦纤维发育不良
Indian J Otolaryngol Head Neck Surg. 2001 Apr;53(2):154-7. doi: 10.1007/BF02991515.
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Frontal sinus mucocele in association with fibrous dysplasia: review and report of two cases.
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