Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Salouti Cornea Research Center, Salouti Eye Clinic, Shiraz, Iran.
Sci Rep. 2024 Oct 14;14(1):24006. doi: 10.1038/s41598-024-74880-w.
This prospective cohort study included 80 healthy candidates for Implantable Collamer Lens (ICL) implantation who underwent biometric assessments with Scheimpflug imaging (the Pentacam-AXL) and swept-source optical coherence tomography (SS-OCT; the IOLMaster-700), both before and 3 months after surgery. The main outcome measures were mean keratometry, anterior chamber depth, axial length, and various intraocular lens (IOL) calculation formulas (Haigis, SRK/T, Hoffer Q, Holladay 1, Barrett Universal 2, and Olsen). The interchangeability of the devices was assessed by generating 95% limits of agreement (95% LoA) and associated Bland-Altman plots. The average age of the participants was 31.5 ± 5.4 years (22-43), with 58 (72.5%) being female. Among the cases analyzed, 11 (13.4%) had incorrect anterior lens surface segmentation using the IOLMaster-700, and 1 case (1.2%) had inappropriate segmentation using the Pentacam-AXL. Postoperative IOL power calculation resulted in readings that were, on average, 0.15 to 0.30 D higher compared to preoperative measurements. The 95% LoAs could differ by up to 0.85 D higher after surgery, indicating weak agreement between pre- and postoperative measurements. There was poor agreement between the IOLMaster-700 and Pentacam-AXL in IOL power calculation for eyes with post-ICL implantation, with a difference of more than 1 D in the 95% LoAs. In conclusion, Scheimpflug imaging was found to be less susceptible than the SS-OCT technique to segmentation errors of the anterior lens surface after ICL implantation. Neither device showed interchangeable results for pre- versus postoperative IOL power calculation. The determination of IOL power by the IOLMaster-700 versus Pentacam-AXL was not interchangeable in eyes with ICL implantation.
本前瞻性队列研究纳入了 80 例拟行可植入 Collamer 透镜（ICL）植入的健康受试者，所有受试者均在术前和术后 3 个月分别行 Scheimpflug 成像（Pentacam-AXL）和扫频源光学相干断层扫描（SS-OCT；IOLMaster-700）生物测量。主要观察指标为平均角膜曲率、前房深度、眼轴长度和各种人工晶状体（IOL）计算公式（Haigis、SRK/T、Hoffer Q、Holladay 1、Barrett Universal 2 和 Olsen）。通过生成 95%一致性界限（95%LoA）和相关 Bland-Altman 图来评估设备的互换性。参与者的平均年龄为 31.5±5.4 岁（22-43 岁），其中 58 例（72.5%）为女性。在分析的病例中，11 例（13.4%）使用 IOLMaster-700 时存在晶状体前表面分割错误，1 例（1.2%）使用 Pentacam-AXL 时存在分割不当。术后 IOL 屈光力计算的读数平均比术前测量值高 0.15 至 0.30 D。术后 95%LoA 最高可相差 0.85 D，表明术前和术后测量之间的一致性较弱。对于 ICL 植入术后的眼睛，IOLMaster-700 和 Pentacam-AXL 之间的 IOL 屈光力计算存在差异，95%LoA 差异超过 1 D，一致性较差。总之，与 SS-OCT 技术相比，ICL 植入术后Scheimpflug 成像受晶状体前表面分割误差的影响较小。两种设备均不能用于 IOL 屈光力的术前与术后测量。在 ICL 植入的眼中，IOLMaster-700 与 Pentacam-AXL 之间的 IOL 屈光力确定不可互换。
