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利用血液学比率:乳腺癌管理的预后见解

Harnessing hematological ratios: prognostic insights for breast cancer management.

作者信息

Coradi Carolina, Panis Carolina

机构信息

Laboratory of Tumor Biology, Centro de Ciências da Saúde, Universidade Estadual do Oeste do Paraná, Rodovia Vitório Traiano, Km2, Francisco Beltrão, Paraná, Brazil.

出版信息

Clin Transl Oncol. 2025 May;27(5):2041-2053. doi: 10.1007/s12094-024-03721-z. Epub 2024 Oct 14.

DOI:10.1007/s12094-024-03721-z
PMID:39402419
Abstract

BACKGROUND

Breast cancer is one of the most lethal diseases affecting women globally. Its progression is influenced by various factors, including the immune system's ability to combat cancer cells. While hematological indices have been recognized as valuable biomarkers for monitoring patients with different types of neoplasms, there remains a considerable gap in research concerning their application in breast cancer.

MATERIAL AND METHODS

To address this, we conducted a systematic review of studies examining hematological indices as prognostic predictors in breast cancer patients.

RESULTS

The majority of studies demonstrate a significant correlation between these indices and survival outcomes, underscoring their potential utility in patient monitoring.

CONCLUSIONS

Hematological-based indexes can be valuable tools for monitoring breast cancer, especially those ongoing poor prognosis scenarios.

摘要

背景

乳腺癌是全球影响女性的最致命疾病之一。其进展受多种因素影响,包括免疫系统对抗癌细胞的能力。虽然血液学指标已被公认为监测不同类型肿瘤患者的有价值生物标志物,但在乳腺癌中的应用研究仍存在相当大的差距。

材料与方法

为解决这一问题,我们对研究血液学指标作为乳腺癌患者预后预测指标的研究进行了系统综述。

结果

大多数研究表明这些指标与生存结果之间存在显著相关性,强调了它们在患者监测中的潜在效用。

结论

基于血液学的指标可成为监测乳腺癌的有价值工具,尤其是在那些预后持续不佳的情况下。

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