Nepal Medical College and Teaching Hospital, Kathmandu, Nepal.
Department of Gastroenterology, Nepal Medical College and Teaching Hospital, Kathmandu, Nepal.
J Med Case Rep. 2024 Oct 15;18(1):498. doi: 10.1186/s13256-024-04813-8.
Gastric antral vascular ectasia is an uncommon clinical disease that affects elder people and is characterized by severe chronic upper gastrointestinal bleeding mainly affecting the gastric antrum. It is generally unusual among patients undergoing maintenance hemodialysis for chronic kidney disease.
Here, we aim to present an uncommon case of incidental diagnosis of the gastric antral vascular ectasia and erosive gastritis in a 71-year-old Hindu male patient belonging to the Gurung ethnicity of Nepal undergoing maintenance hemodialysis due to chronic kidney disease. The patient presented with a history of melena and fatigue. On investigation, a low hemoglobin level of 7.3 gm% was used for blood transfusion. The patient was on regular hemodialysis after admission at our institution. Upper gastrointestinal bleeding was suspected after analyzing patient's history and investigations. Therefore, an upper gastrointestinal endoscopy was performed that showed linear ectatic punctuate lesions radiating from the body of the stomach to the antrum, and hence, an incidental diagnosis of the gastric antral vascular ectasia was made. Initial fluid resuscitation, iron therapy, and a triple regimen were administered. Proper management with argon plasma coagulation therapy was scheduled at another institution due to lack of respective facilities in our institution.
Gastric antral vascular ectasia is an unusual cause of upper gastrointestinal bleeding, primarily affecting the gastric antrum and pylorus with rare cases affecting the duodenum, jejunum, and gastric fundus. It is generally associated with other chronic disease conditions. Several hypotheses have been proposed for the pathogenesis of gastric antral vascular ectasia, especially its association with chronic kidney disease, as in our case, which is considered to be rare. Management varies from medical to endoscopic interventions to even surgery.
Prompt proper diagnosis and treatment for the gastric antral vascular ectasia should be sought, as it is frequently misdiagnosed or missed during upper gastrointestinal endoscopy. Our case report presents a case of gastric antral vascular ectasia in chronic kidney disease undergoing maintenance hemodialysis, which is quite uncommon, as literature has suggested the same point.
胃窦血管扩张症是一种不常见的临床疾病,主要影响老年人,其特征是严重的慢性上消化道出血,主要影响胃窦。在接受慢性肾脏病维持性血液透析的患者中,这种情况通常并不常见。
在这里,我们旨在介绍一个不常见的病例,即一名 71 岁的尼泊尔古隆族印度教男性患者,因慢性肾脏病接受维持性血液透析,偶然诊断出胃窦血管扩张症和糜烂性胃炎。该患者有黑便和乏力的病史。检查发现血红蛋白水平低至 7.3 gm%,需要输血。患者在我们的机构入院后接受定期血液透析。根据患者的病史和检查结果,怀疑上消化道出血。因此,进行了上消化道内镜检查,显示出从胃体向胃窦放射的线性扩张点状病变,因此偶然诊断出胃窦血管扩张症。进行了液体复苏、铁治疗和三联疗法的初始治疗。由于我们机构缺乏相应的设施,计划在另一家机构进行适当的管理,即氩等离子凝固治疗。
胃窦血管扩张症是上消化道出血的不常见原因,主要影响胃窦和幽门,很少影响十二指肠、空肠和胃底。它通常与其他慢性疾病有关。已经提出了几种关于胃窦血管扩张症发病机制的假说,特别是与慢性肾脏病的关联,就像我们的病例一样,这被认为是罕见的。治疗方法从药物治疗到内镜干预甚至手术治疗各不相同。
应尽快对胃窦血管扩张症进行适当的诊断和治疗,因为在上消化道内镜检查中经常误诊或漏诊。我们的病例报告介绍了一例慢性肾脏病维持性血液透析患者的胃窦血管扩张症,这是相当罕见的,正如文献所指出的那样。