Yan Manli, Wu Hai, Zhang Kaiyuan, Gong Ping, Wang Yiting, Wei Hua
Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Meizhou Maternity and Child HealthCare Hospital, Meizhou, China.
Front Nutr. 2024 Sep 30;11:1452371. doi: 10.3389/fnut.2024.1452371. eCollection 2024.
This study aims to explore the correlation between patients with Hashimoto's thyroiditis and food intolerance.
A total of 172 subjects who visited Guangdong Provincial Hospital of Traditional Chinese Medicine between January 2020 and March 2023 were selected and tested for 90 food-specific IgG antibodies. The study group composed 85 individuals diagnosed with Hashimoto's thyroiditis, while the control group consisted of 87 healthy individuals. Data were analyzed to determine the correlation between Hashimoto's thyroiditis and food intolerance.
Among the 85 patients with Hashimoto's thyroiditis, 97.65% exhibited food intolerance, with an average of 15.76 ± 10.61 types of food intolerances. The most common intolerances were to eggs (75.29%), bok choy (71.76%), and milk (65.88%), each exceeding a 60% intolerance rate. In the control group of 87 healthy individuals, the intolerance rate was 95.40%, with an average of 9.57 ± 8.90 types of food intolerances. The most prevalent intolerances in the control group were to bok choy (54.02%) and eggs (52.87%), each exceeding a 50% intolerance rate.
The findings suggest that patients with Hashimoto's thyroiditis are more likely to develop food intolerance compared to the healthy population, which may indicate a correlation between Hashimoto's thyroiditis and food intolerance. Different dietary patterns may affect the activity of the thyroid axis and may even be the cause of autoimmune thyroid disease. The technique of detecting food intolerance IgG antibodies has the potential to be an important reference for dietary interventions in patients with Hashimoto's thyroiditis.
本研究旨在探讨桥本甲状腺炎患者与食物不耐受之间的相关性。
选取2020年1月至2023年3月期间到广东省中医院就诊的172名受试者,检测90种食物特异性IgG抗体。研究组由85名诊断为桥本甲状腺炎的个体组成,对照组由87名健康个体组成。对数据进行分析以确定桥本甲状腺炎与食物不耐受之间的相关性。
在85例桥本甲状腺炎患者中,97.65%表现出食物不耐受,平均食物不耐受种类为15.76±10.61种。最常见的不耐受食物是鸡蛋(75.29%)、小白菜(71.76%)和牛奶(65.88%),每种食物的不耐受率均超过60%。在87名健康个体的对照组中,不耐受率为95.40%,平均食物不耐受种类为9.57±8.90种。对照组中最普遍的不耐受食物是小白菜(54.02%)和鸡蛋(52.87%),每种食物的不耐受率均超过50%。
研究结果表明,与健康人群相比,桥本甲状腺炎患者更易出现食物不耐受,这可能提示桥本甲状腺炎与食物不耐受之间存在相关性。不同的饮食模式可能影响甲状腺轴的活性,甚至可能是自身免疫性甲状腺疾病的病因。检测食物不耐受IgG抗体的技术有可能成为桥本甲状腺炎患者饮食干预的重要参考依据。