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突破障碍:格蒂·科里在生化研究领域的生平与遗产

Breaking Barriers: The Life and Legacy of Gerty Cori in Biochemical Research.

作者信息

Tahir Sara, Tahir Sana, Ganti Latha

机构信息

Physiology and Kinesiology, University of Florida, Gainesville, USA.

Medicine, Orlando College of Osteopathic Medicine, Winter Garden, USA.

出版信息

Cureus. 2024 Sep 14;16(9):e69409. doi: 10.7759/cureus.69409. eCollection 2024 Sep.

Abstract

Gerty Theresa Cori, a remarkable and pioneering biochemist, became the first woman to receive the Nobel Prize in Physiology or Medicine in 1947 for her groundbreaking research in carbohydrate metabolism. Her work, in collaboration with her husband Carl Ferdinand Cori, revolutionized the scientific understanding of carbohydrate metabolism and had a profound impact on medicine and human health. This paper offers a historical vignette of Gerty Cori's life, tracing her journey from her early years in Prague to her pivotal role in transforming biochemistry. It highlights her immense dedication to scientific research, overcoming significant gender-based challenges, and establishing a legacy that continues to inspire. Gerty Cori's contributions to science not only advanced our knowledge of metabolic processes but also paved the way for future generations of researchers, particularly women in science, technology, engineering, and mathematics.

摘要

格蒂·特蕾莎·科里是一位杰出的开创性生物化学家,1947年,她因在碳水化合物代谢方面的开创性研究,成为首位获得诺贝尔生理学或医学奖的女性。她与丈夫卡尔·费迪南德·科里合作开展的研究,彻底改变了科学界对碳水化合物代谢的理解,对医学和人类健康产生了深远影响。本文呈现了格蒂·科里一生的历史片段,追溯了她从布拉格的早年时光到在生物化学变革中所起的关键作用的历程。它突出了她对科学研究的巨大奉献,克服了重大的性别挑战,并留下了持续激励后人的遗产。格蒂·科里对科学的贡献不仅增进了我们对代谢过程的了解,也为后世的研究人员,尤其是从事科学、技术、工程和数学领域的女性,铺平了道路。

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