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三种改良凯斯勒屈肌腱修复技术的生物力学比较:对手术实践和早期主动活动的启示

Biomechanical Comparison of Three Modified Kessler Techniques for Flexor Tendon Repair: Implications in Surgical Practice and Early Active Mobilization.

作者信息

Schellnegger Marlies, Lin Alvin C, Holzer-Geissler Judith C J, Haenel Annika, Pirrung Felix, Hecker Andrzej, Kamolz Lars P, Hammer Niels, Girsch Werner

机构信息

Division of Macroscopy and Clinical Anatomy, Gottfried Schatz Research Center, Medical University of Graz, 8036 Graz, Austria.

COREMED-Cooperative Centre for Regenerative Medicine, Joanneum Research Forschungsgesellschaft mbH, 8036 Graz, Austria.

出版信息

J Clin Med. 2024 Sep 27;13(19):5766. doi: 10.3390/jcm13195766.

Abstract

: Managing flexor tendon injuries surgically remains challenging due to the ongoing debate over the most effective suture technique and materials. An optimal repair must be technically feasible while providing enough strength to allow for early active mobilization during the post-operative phase. This study aimed to assess the biomechanical properties of three modified Kessler repair techniques using two different suture materials: a conventional two-strand and a modified four-strand Kirchmayr-Kessler repair using 3-0 Prolene (2s-KK-P and 4s-KK-P respectively), and a four-strand Kessler-Tsuge repair using 4-0 FiberLoop (4s-KT-FL). : Human flexor digitorum profundus (FDP) tendons were retrieved from Thiel-embalmed prosections. For each tendon, a full-thickness cross-sectional incision was created, and the ends were reattached using either a 2s-KK-P (n = 30), a 4s-KK-P (n = 30), or a 4s-KT-FL repair (n = 30). The repaired tendons were tested using either a quasi-static (n = 45) or cyclic testing protocol (n = 45). Maximum force (F), 2 mm gap force (F), and primary failure modes were recorded. : In both quasi-static and cyclic testing groups, tendons repaired using the 4s-KT-FL approach exhibited higher F and F values compared to the 2s-KK-P or 4s-KK-P repairs. F was significantly higher with a 4s-KK-P versus 2s-KK-P repair, but there was no significant difference in F. Suture pull-out was the main failure mode for the 4s-KT-FL repair, while suture breakage was the primary failure mode in 2s- and 4s-KK-P repairs. : FDP tendons repaired using the 4s-KT-FL approach demonstrated superior biomechanical performance compared to 2s- and 4s-KK-P repairs, suggesting that the 4s-KT-FL tendon repair could potentially reduce the risk of gapping or re-rupture during early active mobilization.

摘要

由于在最有效的缝合技术和材料方面仍存在争议,手术治疗屈指肌腱损伤仍然具有挑战性。最佳修复必须在技术上可行,同时提供足够的强度,以便在术后阶段进行早期主动活动。本研究旨在评估三种改良Kessler修复技术使用两种不同缝合材料的生物力学性能:一种传统的两股和一种使用3-0普理灵的改良四股Kirchmayr-Kessler修复(分别为2s-KK-P和4s-KK-P),以及一种使用4-0 FiberLoop的四股Kessler-Tsuge修复(4s-KT-FL)。:从经蒂尔固定的尸体解剖标本中获取人屈指深肌腱(FDP)。对于每根肌腱,制作一个全层横切口,并使用2s-KK-P(n = 30)、4s-KK-P(n = 30)或4s-KT-FL修复(n = 30)重新连接两端。使用准静态(n = 45)或循环测试方案(n = 45)对修复后的肌腱进行测试。记录最大力(F)、2毫米间隙力(F)和主要失效模式。:在准静态和循环测试组中,与2s-KK-P或4s-KK-P修复相比,使用4s-KT-FL方法修复的肌腱表现出更高的F和F值。4s-KK-P修复的F明显高于2s-KK-P修复,但F没有显著差异。缝线拔出是4s-KT-FL修复的主要失效模式,而缝线断裂是2s-和4s-KK-P修复的主要失效模式。:与2s-和4s-KK-P修复相比,使用4s-KT-FL方法修复的FDP肌腱表现出卓越的生物力学性能,表明4s-KT-FL肌腱修复可能会降低早期主动活动期间出现间隙或再次断裂的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6fc/11477230/38a53de790a9/jcm-13-05766-g001.jpg

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