Villarón-Casales Carlos, de Bernardo Nieves, Alarcón-Jiménez Jorge, López-Malo Daniel, Proaño Belén, Martín-Ruiz Julio, de la Rubia Ortí José Enrique
Biomechanics and Physiotherapy in Sports (BIOCAPS), Faculty of Health Sciences, European University of Valencia, 46001 Valencia, Spain.
Department of Physiotherapy, Catholic University of Valencia, 46900 Valencia, Spain.
J Clin Med. 2024 Sep 28;13(19):5792. doi: 10.3390/jcm13195792.
Parkinson's disease (PD) is a neurodegenerative disorder with high prevalence in men and is characterized by symptoms such as tremors and gait difficulties. This study aimed to determine muscle activation in patients with PD by considering sex differences. This pilot study used analytical, quantitative, observational, and case-control methods. Surface electromyography was used to assess muscle activity during a variant of the Illinois agility test. The study population comprised an experimental group of patients with PD (N = 30) and a control group of healthy individuals without the disease (N = 10). The Illinois agility test revealed significant differences in completion times between the groups. The Parkinson's disease group took longer overall ( = 0.004), especially for standing up ( < 0.001) and sitting down ( = 0.002), than the control group. In the control group, sex influenced gastrocnemius muscle activation, with women showing higher activation (r = -0.87). Women also had greater rectus femoris activation during standing and sitting, with higher activation on the right side when standing (r = -0.66) and the left side when sitting (r = -0.87). In the control group, men exhibited greater activation of the right biceps femoris (r = 0.87). However, in the Parkinson's disease group, sex did not affect muscle activation. Patients with Parkinson's showed lower muscle activation than healthy individuals while standing up, sitting down, and walking.
帕金森病（PD）是一种在男性中患病率较高的神经退行性疾病，其特征包括震颤和步态困难等症状。本研究旨在通过考虑性别差异来确定帕金森病患者的肌肉激活情况。这项初步研究采用了分析性、定量性、观察性和病例对照方法。在伊利诺伊敏捷性测试的一个变体过程中，使用表面肌电图来评估肌肉活动。研究人群包括一个帕金森病患者实验组（N = 30）和一个无该疾病的健康个体对照组（N = 10）。伊利诺伊敏捷性测试显示两组之间在完成时间上存在显著差异。帕金森病组总体花费的时间更长（P = 0.004），尤其是在起身（P < 0.001）和坐下（P = 0.002）时，比对照组更长。在对照组中，性别影响腓肠肌的激活，女性表现出更高的激活水平（r = -0.87）。女性在站立和坐下时股直肌的激活也更强，站立时右侧激活更高（r = -0.66），坐下时左侧激活更高（r = -0.87）。在对照组中，男性右侧股二头肌的激活更强（r = 0.87）。然而，在帕金森病组中，性别并未影响肌肉激活。帕金森病患者在起身、坐下和行走时的肌肉激活低于健康个体。
