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寻找院外心脏骤停复苏期间及之后的可治疗病因。

Seeking a Treatable Cause of Out-of-Hospital Cardiac Arrest during and after Resuscitation.

作者信息

Halablab Saleem M, Reis William, Abella Benjamin S

机构信息

Department of Emergency Medicine and the Center for Resuscitation Science, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

出版信息

J Clin Med. 2024 Sep 28;13(19):5804. doi: 10.3390/jcm13195804.

DOI:10.3390/jcm13195804
PMID:39407863
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11477382/
Abstract

Out-of-hospital cardiac arrest (OHCA) represents a significant global public health burden, characterized by low survival and few established diagnostic tools to guide intervention. OHCA presents with a wide variety of etiologies in a heterogeneous population, posing a clinical challenge to care teams. In this review, we describe evolving research focused on diagnostic approaches to OHCA following resuscitation, including electrocardiography, coronary angiography, computed tomography, ultrasonography, and serologic biomarker assessment. These diagnostic tools have been employed in post-resuscitative efforts for diagnosing ischemic and non-ischemic cardiac, respiratory, neurologic, vascular, traumatic, and metabolic causes of arrest.

摘要

院外心脏骤停(OHCA)是一项重大的全球公共卫生负担,其特点是生存率低且用于指导干预的既定诊断工具很少。OHCA在异质人群中存在多种病因,给护理团队带来了临床挑战。在本综述中,我们描述了针对复苏后OHCA诊断方法的不断发展的研究,包括心电图、冠状动脉造影、计算机断层扫描、超声检查和血清生物标志物评估。这些诊断工具已被用于复苏后的诊断工作,以确定心脏骤停的缺血性和非缺血性心脏、呼吸、神经、血管、创伤和代谢原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e35a/11477382/e0ff7996841e/jcm-13-05804-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e35a/11477382/e0ff7996841e/jcm-13-05804-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e35a/11477382/e0ff7996841e/jcm-13-05804-g001.jpg

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本文引用的文献

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The Recovery of Consciousness via Evidence-Based Medicine and Research (RECOVER) Program: A Paradigm for Advancing Neuroprognostication.基于循证医学与研究的意识恢复(RECOVER)项目:推进神经预后评估的范例
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Admission Total Leukocyte Count as a Predictor of Mortality in Cardiac Intensive Care Unit Patients.入院时白细胞总数作为心脏重症监护病房患者死亡率的预测指标
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Performance of ECG-Derived Digital Biomarker for Screening Coronary Occlusion in Resuscitated Out-of-Hospital Cardiac Arrest Patients: A Comparative Study between Artificial Intelligence and a Group of Experts.
心电图衍生数字生物标志物用于筛查院外心脏骤停复苏患者冠状动脉闭塞的性能:人工智能与一组专家的比较研究
J Clin Med. 2024 Feb 27;13(5):1354. doi: 10.3390/jcm13051354.
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Toxicological profile using mass spectrometry in sudden cardiac arrest survivors admitted to a tertiary centre.应用质谱技术对三级中心收治的心脏骤停幸存者进行毒理学分析。
Resuscitation. 2024 May;198:110197. doi: 10.1016/j.resuscitation.2024.110197. Epub 2024 Apr 4.
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Acute liver failure after out-of-hospital cardiac arrest: An observational study.院外心脏骤停后急性肝功能衰竭:一项观察性研究。
Resuscitation. 2024 Apr;197:110136. doi: 10.1016/j.resuscitation.2024.110136. Epub 2024 Feb 8.
6
Expedited transfer to a cardiac arrest centre for non-ST-elevation out-of-hospital cardiac arrest (ARREST): a UK prospective, multicentre, parallel, randomised clinical trial.非 ST 段抬高院外心搏骤停(ARREST)患者行紧急转运至心搏骤停中心:一项英国前瞻性、多中心、平行、随机临床试验。
Lancet. 2023 Oct 14;402(10410):1329-1337. doi: 10.1016/S0140-6736(23)01351-X. Epub 2023 Aug 27.
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Resuscitation. 2023 Aug;189:109898. doi: 10.1016/j.resuscitation.2023.109898. Epub 2023 Jul 6.
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