Gavrila Ana-Mihaela, Diacon Aurel, Iordache Tanta-Verona, Rotariu Traian, Ionita Mariana, Toader Gabriela
National Institute for Research, Development in Chemistry and Petrochemistry ICECHIM, 202 Spl. Independentei, 060021 Bucharest, Romania.
Military Technical Academy "Ferdinand I", 39-49 George Cosbuc Boulevard, 050141 Bucharest, Romania.
Polymers (Basel). 2024 Sep 24;16(19):2699. doi: 10.3390/polym16192699.
Hazards associated with highly dangerous pollutants/contaminants in water, air, and land resources, as well as food, are serious threats to public health and the environment. Thus, it is imperative to detect or decontaminate, as risk-control strategies, the possible harmful substances sensitively and efficiently. In this context, due to their capacity to be specifically designed for various types of hazardous compounds, the synthesis and use of molecularly imprinted polymers (MIPs) have become widespread. By molecular imprinting, affinity sites with complementary shape, size, and functionality can be created for any template molecule. MIPs' unique functions in response to external factors have attracted researchers to develop a broad range of MIP-based sensors with increased sensitivity, specificity, and selectivity of the recognition element toward target hazardous compounds. Therefore, this paper comprehensively reviews the very recent progress of MIPs and smart polymer applications for sensing or decontamination of hazardous compounds (e.g., drugs, explosives, and biological or chemical agents) in various fields from 2020 to 2024, providing researchers with a rapid tool for investigating the latest research status.
水、空气、土地资源以及食物中与高度危险的污染物相关的危害，对公众健康和环境构成严重威胁。因此，作为风险控制策略，必须灵敏且高效地检测或去除可能的有害物质。在此背景下，由于分子印迹聚合物（MIP）能够针对各类有害化合物进行特定设计，其合成与应用已广泛开展。通过分子印迹，可以为任何模板分子创建具有互补形状、大小和功能的亲和位点。MIP对外部因素的独特响应功能吸引了研究人员开发一系列基于MIP的传感器，这些传感器对目标有害化合物的识别元件具有更高的灵敏度、特异性和选择性。因此，本文全面综述了2020年至2024年期间MIP和智能聚合物在各个领域用于检测或去除有害化合物（如药物、爆炸物以及生物或化学制剂）的最新进展，为研究人员提供了一个快速了解最新研究状况的工具。
