Smith T, Zeeberg I, Sjö O
Eur Neurol. 1986;25(1):67-73. doi: 10.1159/000115989.
We studied 8 patients with definite multiple sclerosis (3 with acute relapse, 5 with progression), and 2 patients with acute optic neuritis, who were treated with methylprednisolone infusions, 1 g daily for 3 days. Visual, brain stem-auditory and somatosensory-evoked potentials were used to test the effect of therapy. There were no manifest changes of the evoked potentials parameters parallel to the clinical effect of high-dose therapy.
我们研究了8例明确诊断为多发性硬化症的患者（3例急性复发，5例病情进展）以及2例急性视神经炎患者，他们接受了甲基泼尼松龙静脉输注治疗，每日1克，共3天。使用视觉、脑干听觉和体感诱发电位来测试治疗效果。与高剂量治疗的临床效果平行，诱发电位参数没有明显变化。
