Cesar Cinthia Gonçalves Lenz, Marchi Pedro Henrique, Amaral Andressa Rodrigues, Príncipe Leonardo de Andrade, Carmo Adrielly Aparecida do, Zafalon Rafael Vessecchi Amorim, Miyamoto Nelson Nobuhiro, Garcia Nury Aymée Collona Rodriguez, Balieiro Júlio Cesar de Carvalho, Vendramini Thiago Henrique Annibale
Pet Nutrology Research Center (CEPEN Pet), Department of Animal Nutrition and Production, School of Veterinary Medicine and Animal Science, University of Sao Paulo, Pirassununga 13635-000, Brazil.
Veterinary Nutrology Service, Veterinary University Hospital, School of Veterinary Medicine and Animal Science, University of Sao Paulo, Sao Paulo 05508-270, Brazil.
Animals (Basel). 2024 Oct 4;14(19):2859. doi: 10.3390/ani14192859.
Food allergy triggers an immune response to dietary proteins, resulting in food rejection and dermatological and gastrointestinal manifestations. The preferred therapies include diets with hydrolyzed proteins or unusual single-source proteins, with insect protein emerging as a promising option, with no reported allergic reactions in dogs with a food allergy. In this case study, the effects of including black soldier fly larva (BSFL) meal were observed in a 5-year-old spayed beagle previously diagnosed with a food allergy. The objective was to assess the potential of BSFL meal as an adjunct in treating a food allergy. As part of the protocol, two nutritionally very similar diets were used, differing only in the protein source: the control diet, with poultry by-product meal; and the BSFL diet, which completely replaced the poultry by-product meal. After a 12-day adaptation period to the BSFL diet, the dog showed no gastrointestinal changes, maintaining an adequate fecal score and no clinical signs of the disease. A challenge test with the control diet resulted in episodic gastrointestinal symptoms, which were reversed within two days by reintroducing the BSFL diet. The BSFL protein-based diet was effective in controlling the dog's clinical signs.
食物过敏会引发对膳食蛋白质的免疫反应,导致食物拒食以及皮肤和胃肠道症状。首选治疗方法包括食用含水解蛋白或特殊单一来源蛋白质的饮食,昆虫蛋白正成为一种有前景的选择,在患有食物过敏的犬中未报告有过敏反应。在本病例研究中,观察了在一只先前被诊断患有食物过敏的5岁绝育比格犬中添加黑水虻幼虫(BSFL)粉的效果。目的是评估BSFL粉作为辅助治疗食物过敏的潜力。作为方案的一部分,使用了两种营养上非常相似的饮食,仅蛋白质来源不同:对照饮食,含家禽副产品粉;以及BSFL饮食,完全替代了家禽副产品粉。在对BSFL饮食进行12天的适应期后,该犬未出现胃肠道变化,粪便评分保持正常,且无疾病临床症状。用对照饮食进行激发试验导致间歇性胃肠道症状,重新引入BSFL饮食后两天内症状缓解。基于BSFL蛋白的饮食有效地控制了该犬的临床症状。