Hässig Michael, Biner Natascha, Gerspach Christian, Hertzberg Hubertus, Kühni Michaela, Schelling Claude, Liesegang Annette
Department of Farm Animals, University of Zurich, Winterthurerstrasse 270, CH-8057 Zurich, Switzerland.
Institute of Parasitology, University of Zurich, Winterthurerstrasse 270, CH-8057 Zurich, Switzerland.
Animals (Basel). 2024 Oct 9;14(19):2915. doi: 10.3390/ani14192915.
Between 2006 and 2014, 10 cases of in yaks with calcium carbonate uroliths were confirmed in Switzerland, and at the same time, a sixfold calcium overhang in roughage in an affected farm was evident. The purpose of this study was the question of whether in yaks in the alpine regions of Switzerland poses a husbandry risk. The hypothesis was that elevated calcium levels in roughage led to and, thus, the formation of calcium carbonate stones.
Blood samples from 99 animals from 10 farms were examined ( = 6 problem farms; n = 4 control farms). Several metabolites were analyzed in the blood and urine. In addition, roughage, soil, and water samples were analyzed. The farms were distributed within different regions of Switzerland.
This study revealed different Ca:P ratios, from 1.56 to 7.74:1, in the forages and mild hypercalcemia in the animals of the problem farms. In a univariate analysis of the problem versus control farms, about 20 other significant factors emerged. Multivariate analysis showed that altitude, CP (crude protein), P, Mg, NDF, and ADF in the diet are important factors. Based on analysis of the pedigree, there was no evidence of an obvious genetic background of .
A limitation of this study is the small number of yaks in Switzerland.
The question of whether in yaks in alpine Switzerland poses a husbandry risk can be answered affirmatively. Calcium-rich forages play a crucial role in this multifactorial process.
2006年至2014年期间，瑞士确诊了10例牦牛患碳酸钙尿石症的病例，与此同时，在一个受影响的农场中，粗饲料中的钙含量明显高出六倍。本研究的目的是探讨瑞士高山地区牦牛的[病症名称未给出]是否构成养殖风险。假设是粗饲料中钙水平升高导致了[病症名称未给出]，进而形成碳酸钙结石。
对来自10个农场的99头动物的血液样本进行了检测（其中6个为问题农场；4个为对照农场）。对血液和尿液中的几种代谢物进行了分析。此外，还对粗饲料、土壤和水样进行了分析。这些农场分布在瑞士的不同地区。
本研究揭示了牧草中不同的钙磷比，从1.56到7.74:1，以及问题农场动物中存在轻度高钙血症。在对问题农场与对照农场的单变量分析中，出现了约20个其他显著因素。多变量分析表明，日粮中的海拔、粗蛋白（CP）、磷、镁、中性洗涤纤维（NDF）和酸性洗涤纤维（ADF）是重要因素。基于系谱分析，没有证据表明[病症名称未给出]有明显的遗传背景。
本研究的一个局限性是瑞士牦牛数量较少。
瑞士高山地区牦牛的[病症名称未给出]是否构成养殖风险这一问题可以肯定地回答。富含钙的牧草在这一多因素过程中起着关键作用。
