Bhat Vasudeva K, Vijayasekharan Kalasekhar, Usman Nawaz, Kumar Naveena A N
Division of Pediatric Hematology and Oncology, Manipal Comprehensive Cancer Care Center, Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India.
Department of Surgical Oncology, Manipal Comprehensive Cancer Care Center, Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India.
South Asian J Cancer. 2022 Nov 2;13(3):220-223. doi: 10.1055/s-0042-1757426. eCollection 2024 Jul.
Naveena A.N. KumarPrimary malignant germ cell tumor (GCT) of the mediastinum is a rare entity with an incidence ranging from 1 to 2% of all childhood cancers. Though a few cases of bone metastasis from mediastinal GCTs have been reported, synchronous whole sternal metastasis from primary malignant mediastinal GCTs is very rare. We report such a rare manifestation in a teenager, emphasizing the need for a multidisciplinary treatment approach with neoadjuvant chemotherapy, surgical expertise for en bloc excision of the mediastinal mass along with whole sternal resection, and reconstruction in a dedicated cancer care center for better oncological outcomes.
纳维娜·A.N.·库马尔
纵隔原发性恶性生殖细胞肿瘤(GCT)是一种罕见的疾病,在所有儿童癌症中的发病率为1%至2%。虽然已有少数纵隔GCT发生骨转移的病例报道,但原发性恶性纵隔GCT同时发生全胸骨转移非常罕见。我们报告了一名青少年患者的这种罕见表现,强调需要采用多学科治疗方法,包括新辅助化疗、具备整块切除纵隔肿块及全胸骨切除的手术专业技术,以及在专门的癌症治疗中心进行重建,以获得更好的肿瘤学治疗效果。