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[快速综述:虫媒病毒控制策略的有效性 快速系统综述:控制虫媒病毒策略在防治虫媒病毒病方面的有效性]

[Rapid review: effectiveness of the strategy for arbovirus controlRevisión sistemática rápida: efectividad de la estrategia de control con en la lucha contra las arbovirosis].

作者信息

Angotti Alanis Amorim, da Silva João Gabriel Sanchez Tavares, Yonekura Tatiana, Figueiró Mabel Fernandes

机构信息

Pesquisadora autônoma   Pesquisadora autônoma.

Instituto de Pesquisa HCor   Instituto de Pesquisa, HCor.

出版信息

Rev Panam Salud Publica. 2024 Oct 15;48:e98. doi: 10.26633/RPSP.2024.98. eCollection 2024.

DOI:10.26633/RPSP.2024.98
PMID:39411028
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11476870/
Abstract

OBJECTIVE

To identify and synthesize evidence of the effectiveness and cost-effectiveness of the methodology for reducing cases of arboviral infection.

METHODOLOGY

Rapid systematic review. A search of five online portals and bibliographic databases was conducted in February 2022. Two reviewers conducted the selection stages, with any disagreements resolved by a third investigator. Data were extracted by one reviewer and subsequently checked by another. The inclusion criteria were studies describing the cost-effectiveness and effectiveness of the methodology, based on field interventions, published in Portuguese, English, and Spanish, with no restrictions on date of publication.

RESULTS

Four studies were included: one cluster randomized trial, two quasi-experimental studies, and one pre-post study, published between 2019 and 2021 in four countries. The included studies reported effectiveness for some of the outcomes of interest, such as a reduction in the incidence of dengue, Zika, and chikungunya cases. Although no experimental studies addressing the cost-effectiveness of the strategy were identified, some modeling studies have demonstrated potential cost-benefit of this methodology.

CONCLUSION

Considering the results of the included studies, has the potential to be an economically effective strategy that leads to reductions in the incidence of dengue, Zika, and chikungunya. Nevertheless, this strategy cannot yet be recommended as a public policy; additional large-scale studies with high methodological quality are still needed to inform political decision-making.

摘要

目的

识别并综合关于减少虫媒病毒感染病例方法的有效性和成本效益的证据。

方法

快速系统评价。2022年2月对五个在线平台和文献数据库进行了检索。两名评审员进行筛选阶段工作,如有分歧由第三名研究人员解决。数据由一名评审员提取,随后由另一名评审员检查。纳入标准为基于现场干预、以葡萄牙语、英语和西班牙语发表、对发表日期无限制、描述该方法成本效益和有效性的研究。

结果

纳入四项研究:一项整群随机试验、两项准实验研究和一项前后对照研究,于2019年至2021年期间在四个国家发表。纳入的研究报告了一些感兴趣结局的有效性,如登革热、寨卡病毒病和基孔肯雅热病例发病率的降低。虽然未发现针对该策略成本效益的实验性研究,但一些模型研究已证明该方法具有潜在的成本效益。

结论

考虑到纳入研究的结果,该方法有可能成为一种经济有效的策略,可降低登革热、寨卡病毒病和基孔肯雅热的发病率。然而,该策略目前尚不能作为公共政策推荐;仍需要更多方法学质量高的大规模研究为政治决策提供依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef77/11476870/8fee8831e397/rpsp-48-e98_Figure1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef77/11476870/8fee8831e397/rpsp-48-e98_Figure1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef77/11476870/8fee8831e397/rpsp-48-e98_Figure1.jpg

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本文引用的文献

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Trials. 2022 Mar 2;23(1):185. doi: 10.1186/s13063-022-05997-4.
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Effectiveness of Wolbachia-infected mosquito deployments in reducing the incidence of dengue and other Aedes-borne diseases in Niterói, Brazil: A quasi-experimental study.巴西尼泰罗伊的沃尔巴克氏体感染蚊子部署降低登革热和其他伊蚊传播疾病发病率的效果:一项准实验研究。
PLoS Negl Trop Dis. 2021 Jul 12;15(7):e0009556. doi: 10.1371/journal.pntd.0009556. eCollection 2021 Jul.
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Efficacy of Wolbachia-Infected Mosquito Deployments for the Control of Dengue.
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