Ali Nur Shidaa Mohd, Ngalimat Mohamad Syazwan, Saad Mohd Zamri, Azmai Mohammad Noor Amal, Salleh Annas, Zulperi Zarirah, Yasin Ina Salwany Md
Laboratory of Aquatic Animal Health and Therapeutics, Institute of Bioscience, Universiti Putra Malaysia UPM, 43400 Serdang, Selangor, Malaysia.
Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia UPM, 43400 Serdang, Selangor, Malaysia.
Data Brief. 2024 Sep 26;57:110977. doi: 10.1016/j.dib.2024.110977. eCollection 2024 Dec.
Previous studies have proven that red hybrid tilapia ( sp.) vaccinated with a feed-based bivalent vaccine incorporating the formalin-killed whole organisms and mixed with 10 % palm oil showed good protection against streptococcosis and aeromoniasis diseases. However, the molecular mechanisms related to the induction of fish's immunological responses after vaccination are poorly investigated. Therefore, a transcriptomic study using the hindgut of red hybrid tilapia after vaccination was conducted, as the gut plays a role in antigen uptake and nutrient absorption. The transcriptome dataset has the potential to provide an understanding of the early induction of immunological responses in red hybrid tilapia after vaccination. Here, the vaccinated and control red hybrid tilapia's hindgut ribonucleic acid sequencing (RNA-seq) dataset was presented, which are available in the National Center for Biotechnology Information (NCBI) database with accession number PRJNA1014699.
先前的研究已经证明，用含有福尔马林灭活的全菌体并与10%棕榈油混合的饲料型二价疫苗接种的红罗非鱼（品种）对链球菌病和气单胞菌病具有良好的保护作用。然而，接种疫苗后鱼类免疫反应诱导相关的分子机制研究较少。因此，对接种疫苗后的红罗非鱼后肠进行了转录组学研究，因为肠道在抗原摄取和营养吸收中发挥作用。转录组数据集有可能提供对接种疫苗后红罗非鱼免疫反应早期诱导的理解。在此，展示了接种疫苗和对照的红罗非鱼后肠核糖核酸测序（RNA-seq）数据集，这些数据集可在国家生物技术信息中心（NCBI）数据库中获取，登录号为PRJNA1014699。
