Scrotal cellular angiofibroma: A case report and review of the literature.

Scrotal cellular angiofibroma (CAF) is a rare, benign, soft-tissue paratesticular tumor that has been sporadically reported previously. We present a case of a 55-year old male with a scrotal mass ultimately diagnosed with scrotal CAF. Immunohistochemical analysis stained positively for desmin, CD34, and estrogen receptor. Our series is one of the only published to date demonstrating desmin-positive paratesticular CAF. Diagnosis of CAF remains difficult due to the sparsity of paratesticular CAF, its similar characteristics to spindle cell lipoma (SCL), and variability in immunohistochemical reporting.