Balaji Lavanya, Ravella Venkatasubramanyam Nandhini, Umapathy Navin, Easwaran Subbalakshmi, Prabhakaran Neelusree
Department of Microbiology, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Department of Pediatrics, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Cureus. 2024 Sep 15;16(9):e69472. doi: 10.7759/cureus.69472. eCollection 2024 Sep.
Edward Jenner, born in 1749 in Berkeley, Gloucestershire, England is widely recognized as the pioneer of the smallpox vaccine, a breakthrough that paved the way for the eventual eradication of the disease. This article traces Jenner's journey from his early education and apprenticeship under renowned surgeon John Hunter to his groundbreaking work on vaccination. Jenner's keen observations led him to hypothesize that cowpox could provide immunity against smallpox, which he confirmed through an experiment in 1796. Despite initial skepticism and the continued practice of variolation, Jenner's findings gained acceptance, and his work laid the foundation for modern immunology. The article also explores Jenner's personal life, his contributions to the medical community, and the eventual global impact of his work, culminating in the eradication of smallpox. Jenner's legacy is a testament to the power of scientific inquiry and its transformative effect on public health.
爱德华·詹纳于1749年出生在英国格洛斯特郡的伯克利,他被广泛认为是天花疫苗的先驱,这一突破为最终根除该疾病铺平了道路。本文追溯了詹纳从早期教育和在著名外科医生约翰·亨特手下当学徒,到他在疫苗接种方面的开创性工作的历程。詹纳敏锐的观察使他推测牛痘可以提供对天花的免疫力,他在1796年通过一项实验证实了这一点。尽管最初遭到怀疑,并且人痘接种仍在继续,但詹纳的发现还是得到了认可,他的工作为现代免疫学奠定了基础。文章还探讨了詹纳的个人生活、他对医学界的贡献以及他的工作最终在全球产生的影响,最终导致天花被根除。詹纳的遗产证明了科学探究的力量及其对公共卫生的变革性影响。