Matsuura H, Kudo M, Ikeda Y, Isayama K, Nakazawa S
J Neurosurg. 1986 Jan;64(1):125-7. doi: 10.3171/jns.1986.64.1.0125.
Brain abscesses in rats were produced by intra-arterial injection of septic homologous blood clot emboli. The production rate was 100% and the histopathological features closely resembled those seen in other animal models and in spontaneously occurring brain abscesses in humans. This small-animal model may be useful for systematic study of the development of brain abscesses as well as for evaluation of various therapeutic procedures.
