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为期八周的口服铁补充剂改善了缺铁性贫血年轻女性的姿势控制能力。

Eight weeks of oral iron supplementation improves postural control in young women with iron deficiency anemia.

作者信息

Harrabi Mohamed Achraf, Fendri Thouraya, Chaari Fatma, Ayed Rahma, Mezghani Ines, Kallel Choumous, Rebai Haithem, Turki Mouna, Ayadi Fatma, Sahli Sonia

机构信息

Research Laboratory Education, Motricité, Sport et Santé, EM2S, LR19JS01, High Institute of Sport and Physical Education of Sfax, University of Sfax, 3000, Sfax, Tunisia.

Sport, Physical Activity, Rehabilitation and Movement for Performance and Health (SAPRéM), Université d'Orléans, Orléans, France.

出版信息

Eur J Clin Nutr. 2025 Mar;79(2):156-160. doi: 10.1038/s41430-024-01522-9. Epub 2024 Oct 16.

Abstract

OBJECTIVE

This study aimed to explore the effect of 8-week oral supplementation on postural control in young women with iron deficiency anemia (IDA).

METHODS

This study involved 15 women with IDA who received 160 mg of elemental iron daily in the form of dried ferrous sulfate capsules (80 mg twice daily) taken in two divided doses for 8 weeks. The mean velocity of oscillations of the center of pressure (CoPv) was recorded to evaluate postural control pre- and post-supplementation. In addition, simple reaction time (SRT) and weight discrimination tests were performed to assess attentional capacity and proprioceptive acuity, respectively.

RESULTS

This study revealed significant increases (P < 0.001, mean difference = 1.83, 95% CI: -17.25; -9.42) in proprioceptive acuity values, as well as decreases in CoPv [firm (EO (P < 0.01, mean difference = 0.52, 95% CI: 0.69; 2.92), EC (P < 0.05, mean difference = 0.75, 95% CI: 0.24; 3.45)) and foam (EO (P < 0.001, mean difference = 0.64, 95% CI: 1.71; 4.44) ; EC (P < 0.001, mean difference = 1.04, 95% CI: 3.51; 7.97))] and SRT (P < 0.001, mean difference = 59.31, 95% CI: 103.02; 168.71) values post-supplementation compared to pre-supplementation.

CONCLUSION

This study showed significant improvements in postural control in young women with IDA after 8 weeks of oral iron supplementation. These improvements were probably related to the enhanced bioavailability of iron, which may have influenced neural processes inducing improvements in attention capacity and proprioceptive acuity.

摘要

目的

本研究旨在探讨为期8周的口服补充剂对缺铁性贫血(IDA)年轻女性姿势控制的影响。

方法

本研究纳入了15名IDA女性,她们每天以硫酸亚铁干胶囊的形式服用160毫克元素铁(80毫克,每日两次),分两次服用,持续8周。记录压力中心振荡的平均速度(CoPv),以评估补充前后的姿势控制。此外,分别进行简单反应时间(SRT)和重量辨别测试,以评估注意力容量和本体感觉敏锐度。

结果

本研究显示,与补充前相比,补充后本体感觉敏锐度值显著增加(P < 0.001,平均差异 = 1.83,95%置信区间:-17.25;-9.42),CoPv [稳定(睁眼(EO)(P < 0.01,平均差异 = 0.52,95%置信区间:0.69;2.92),闭眼(EC)(P < 0.05,平均差异 = 0.75,95%置信区间:0.24;3.45))和泡沫(EO(P < 0.001,平均差异 = 0.64,95%置信区间:1.71;4.44);EC(P < 0.001,平均差异 = 1.04,95%置信区间:3.51;7.97))] 和SRT(P < 0.001,平均差异 = 59.31,95%置信区间:103.02;168.71)值降低。

结论

本研究表明,口服铁补充剂8周后,IDA年轻女性的姿势控制有显著改善。这些改善可能与铁生物利用度的提高有关,这可能影响了神经过程,从而导致注意力容量和本体感觉敏锐度的改善。

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