Kazantsev Anton, Korotkikh Alexander, Leader Roman, Artyukhov Sergey, Roshkovskaya Lyudmila, Unguryan Vladimir, Chernyavin Maxim, Yury Belov
Kostroma Regional Clinical Hospital Named After Korolev E.I, Kostroma, Russian Federation.
Clinic of Cardiac Surgery of the Amur State Medical Academy of the Ministry of Health of Russia, Blagoveshchensk, Russian Federation.
Indian J Thorac Cardiovasc Surg. 2024 Nov;40(6):675-683. doi: 10.1007/s12055-024-01753-2. Epub 2024 Jun 19.
This is a retrospective analysis of the results of carotid endarterectomy (CEA) in different age groups.
This cohort, comparative, retrospective, open-label study for the period from 2008 to 2020 included 7248 patients with hemodynamically significant stenoses of the internal carotid artery (ICA), who underwent CEA. According to the classification of the World Health Organization, patients were divided into groups depending on age: up to 44 years-young age ( = 84); 45-60 years-middle age ( = 1635); 61-75-elderly age ( = 4817); over 75 years-senile age ( = 712).
In terms of the frequency of hospital complications, the group of patients over 75 years of age experienced the largest number of cardiovascular events. One year after surgery, there were no significant differences in the incidence of complications between groups: death (group 1, 1.2%; group 2, 0.5%; group 3, 0.4%; group 4, 1%; = 0.14), myocardial infarction (group 1, 1.2%; group 2, 0.3%; group 3, 0.14%; group 4, 0.3%; = 0.12), stroke (group 1, 0%; group 2, 0.3%; group 3, 0.1%; group 4, 0.4%; = 0.32).
The largest number of adverse cardiovascular events after CEA are observed among patients over 75 years of age, which is due to the high frequency of multivessel coronary lesions, atrial fibrillation, and the severity of the comorbidities. One year after surgery, there were no significant differences in the incidence of complications between groups.
这是一项对不同年龄组颈动脉内膜切除术（CEA）结果的回顾性分析。
这项队列、比较、回顾性、开放标签研究涵盖了2008年至2020年期间7248例患有颈内动脉（ICA）血流动力学显著狭窄并接受CEA的患者。根据世界卫生组织的分类，患者按年龄分为几组：44岁及以下为青年组（n = 84）；45至60岁为中年组（n = 1635）；61至75岁为老年组（n = 4817）；75岁以上为高龄组（n = 712）。
就医院并发症发生率而言，75岁以上患者组经历的心血管事件数量最多。术后一年，各组间并发症发生率无显著差异：死亡（第1组，1.2%；第2组，0.5%；第3组，0.4%；第4组，1%；P = 0.14），心肌梗死（第1组，1.2%；第2组，0.3%；第3组，0.14%；第4组，0.3%；P = 0.12），中风（第1组，0%；第2组，0.3%；第3组，0.1%；第4组，0.4%；P = 0.32）。
CEA术后发生不良心血管事件数量最多的是75岁以上患者，这是由于多支冠状动脉病变、心房颤动的高发生率以及合并症的严重程度所致。术后一年，各组间并发症发生率无显著差异。
