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英国的合成生物学概况。

Synthetic biology landscape in the UK.

作者信息

Wachter Georg K A, Gallup Olivia, Bayne James, Horsfall Louise

机构信息

Department Of Mechanical Engineering, Exhibition Road, Kensington, London, SW7 2BX, United Kingdom.

Nucleate, 88 Gordon Street #401, Brighton, MA, 02135, USA.

出版信息

Biotechnol Notes. 2022 Aug 9;3:70-74. doi: 10.1016/j.biotno.2022.07.002. eCollection 2022.

Abstract

The UK is home to a vibrant and diverse synthetic biology community. Many of its successes in research innovation and technological commercialisation can be attributed to a strong base of dedicated academics, investors, industrial leadership, and policymakers. Here, we give an overview of the organisations making up the network that have been key to these successes and the roles that they play within the different levels of the community. We start with a brief history of synthetic biology in the UK and continue by describing the progression of the societies and institutions that were set up, with particular focus on the UK's active student and entrepreneurship scene, as well as centres of research. We then contextualise the UK's growing bioeconomy, detailing government trajectories of planned innovation and how these coincide with research translation. The path to commercialisation for researchers is put into comparison to that of the US, the world leader in synthetic biology and its translation, highlighting aspects that differentiate the UK globally. Finally, we conclude with a bright outlook on the current velocity of progress and the state of the community.

摘要

英国是充满活力和多元化的合成生物学界的所在地。其在研究创新和技术商业化方面的许多成功都可归功于一批敬业的学者、投资者、行业领袖和政策制定者所奠定的坚实基础。在此,我们概述了构成该网络的各个组织,这些组织是取得这些成功的关键,以及它们在不同层面的社区中所发挥的作用。我们首先简要介绍英国合成生物学的历史,接着描述已成立的协会和机构的发展历程,特别关注英国活跃的学生和创业领域以及研究中心。然后,我们将英国不断发展的生物经济置于背景之中,详细阐述政府计划创新的轨迹以及这些轨迹与研究转化的契合点。将研究人员的商业化之路与合成生物学及其转化领域的全球领导者美国进行比较,突出英国在全球范围内的独特之处。最后,我们对当前的发展速度和社区状况给出了乐观的展望。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e721/11446367/8d1d3a141e90/gr1.jpg

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