Sharma Preethi N, Hande Alka, Patil Swati K, Sonone Archana M, Pakhale Aayushi, Kalmegh Padmashri P, Khan Samiha
Oral and Maxillofacial Pathology, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Oral Pathology and Microbiology, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus. 2024 Sep 16;16(9):e69544. doi: 10.7759/cureus.69544. eCollection 2024 Sep.
Epithelial-myoepithelial carcinoma (EMC) is an uncommon malignancy that usually originates in the salivary glands. Its occurrence in the maxillary sinus is rare. We present a case of a 68-year-old male patient who has been experiencing swelling in the upper right back region of the jaw for the past three months. A computerized tomography scan of the paranasal sinus suggested the possibility of a malignant neoplastic mass originating from the right maxillary sinus, with significant local extension and bony erosions. Histopathology examination of EMC revealed a tubular morphology lined with inner luminal cells and outer clear cells of myoepithelial origin. For confirmatory diagnosis, immunohistochemistry (IHC) markers were applied, in which the inner lining of cells was positive for S100, while the outer lining of cells tested positive for both p63 and S100. The patient underwent a hemi-maxillectomy of the right side under general anesthesia.
上皮-肌上皮癌（EMC）是一种罕见的恶性肿瘤，通常起源于唾液腺。它发生在上颌窦的情况很罕见。我们报告一例68岁男性患者，在过去三个月里右上颌后区一直肿胀。鼻窦计算机断层扫描提示可能存在起源于右上颌窦的恶性肿瘤性肿块，有明显的局部扩展和骨质侵蚀。EMC的组织病理学检查显示为管状形态，内衬管腔细胞，外层为肌上皮来源的透明细胞。为进行确诊，应用了免疫组织化学（IHC）标志物，其中细胞内衬对S100呈阳性，而细胞外层对p63和S100均呈阳性。患者在全身麻醉下接受了右侧半上颌骨切除术。
