Roseti Livia, Borciani Giorgia, Grassi Francesco, Desando Giovanna, Gambari Laura, Grigolo Brunella
RAMSES Laboratory, Rizzoli RIT-Research, Innovation & Technology Department, Istituto di Ricerca Codivilla Putti, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Front Nutr. 2024 Oct 2;11:1445955. doi: 10.3389/fnut.2024.1445955. eCollection 2024.
Nutraceuticals are gaining popularity as they can contribute to bone health by delaying the onset or slowing down the progression of pathological bone loss. Osteoporosis's bone loss is a concern for older adults and a crucial aspect of aging. Maintaining healthy bones is the key to living a full and active life. Our review explores the current knowledge on the role of nutraceuticals in preventing osteoporosis by focusing on three main aspects. First, we provide an overview of osteoporosis. Second, we discuss the latest findings on natural nutraceuticals and their efficacy in reducing bone loss, emphasizing clinical trials. Third, we conduct a structured analysis to evaluate nutraceuticals' pros and cons and identify translational gaps. In conclusion, we must address several challenges to consolidate our knowledge, better support clinicians in their prescriptions, and provide people with more reliable nutritional recommendations to help them lead healthier lives.
营养保健品正越来越受欢迎,因为它们可以通过延缓病理性骨质流失的发生或减缓其进展来促进骨骼健康。骨质疏松症导致的骨质流失是老年人关注的问题,也是衰老的一个关键方面。保持骨骼健康是过上充实而积极生活的关键。我们的综述通过关注三个主要方面来探索营养保健品在预防骨质疏松症方面的现有知识。首先,我们概述骨质疏松症。其次,我们讨论天然营养保健品的最新发现及其在减少骨质流失方面的功效,重点是临床试验。第三,我们进行结构化分析以评估营养保健品的优缺点,并找出转化差距。总之,我们必须应对几个挑战,以巩固我们的知识,更好地支持临床医生开处方,并为人们提供更可靠的营养建议,以帮助他们过上更健康的生活。