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解析植物化学疗法的当前突破:一项系统综述。

Unraveling current breakthroughs in phytochemical therapeutics: A systematic review.

作者信息

Zawawi Muhammad Hamizan, Azhani-Amran Siti, Abdullah Zuraidah, Safuan Sabreena

机构信息

Biomedicine Programme, School of Health Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.

Nutrition Programme, School of Health Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.

出版信息

Biotechnol Notes. 2024 Jun 6;5:100-110. doi: 10.1016/j.biotno.2024.05.001. eCollection 2024.

DOI:10.1016/j.biotno.2024.05.001
PMID:39416699
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11446353/
Abstract

, also known as the Kulim tree or Garlic tree, has been consumed by the local communities in Southeast Asia as traditional spice using its old leaves, stem bark, and seeds. The locals also used Kulim tree parts as conventional alternative to treat many diseases such as hemorrhoids, leprosy, diabetes, and diarrhea. However, there was limited scientific evidence to support these traditional claims. Therefore, this systematic review aims to present and evaluate a detailed overview of the phytochemical constituents of from previous existing studies, shedding light on their chemical composition, bioactivity, and potential applications. In addition, current studies regarding are still on a fundamental level. Hence, we aim that this review will reveal the research gap from the previous literature and provide an insight to implement a new research approach in the future. A literature search was conducted using four databases: ScienceDirect, Scopus, Web of Science, and PubMed. The articles were screened and data were extracted based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guideline. 8 studies satisfied the inclusion criteria that focused on the phytochemicals from . The major phytochemical compound reported was phenolic compound. S. borneensis also exhibits several therapeutic outcomes such as antioxidant, antimicrobial, and anticancer but current studies are not enough to support the claims regarding health benefit. In conclusion, this review highlights the current understanding of phytochemical composition and its therapeutic applications which are important in preventing human diseases especially non-communicable diseases.

摘要

也被称为古林树或大蒜树,东南亚当地社区一直将其老叶、茎皮和种子作为传统香料食用。当地人还将古林树的部分用作传统替代品来治疗多种疾病,如痔疮、麻风病、糖尿病和腹泻。然而,支持这些传统说法的科学证据有限。因此,本系统综述旨在展示和评估先前现有研究中关于[植物名称]植物化学成分的详细概述,阐明其化学成分、生物活性和潜在应用。此外,目前关于[植物名称]的研究仍处于基础层面。因此,我们旨在通过本综述揭示先前文献中的研究空白,并为未来实施新的研究方法提供见解。使用四个数据库进行了文献检索:ScienceDirect、Scopus、Web of Science和PubMed。根据PRISMA(系统评价和Meta分析的首选报告项目)指南对文章进行筛选并提取数据。8项研究符合纳入标准,重点关注[植物名称]中的植物化学物质。报告的主要植物化学化合物是酚类化合物。[植物名称]还表现出多种治疗效果,如抗氧化、抗菌和抗癌,但目前的研究不足以支持关于[植物名称]健康益处的说法。总之,本综述突出了目前对[植物名称]植物化学成分及其治疗应用的理解,这对于预防人类疾病尤其是非传染性疾病具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44b9/11446353/b493dc8f5058/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44b9/11446353/cb939fc524e5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44b9/11446353/ceda106cfedd/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44b9/11446353/bb93a885fd3b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44b9/11446353/b493dc8f5058/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44b9/11446353/cb939fc524e5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44b9/11446353/ceda106cfedd/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44b9/11446353/bb93a885fd3b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44b9/11446353/b493dc8f5058/gr4.jpg

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Cytotoxic Activity, Cell Cycle Inhibition, and Apoptosis-Inducing Potential of (Lady Fern) with Its Phytochemical Profiling.
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Dietary Polyphenols and Their Role in Oxidative Stress-Induced Human Diseases: Insights Into Protective Effects, Antioxidant Potentials and Mechanism(s) of Action.膳食多酚及其在氧化应激诱导的人类疾病中的作用:对保护作用、抗氧化潜力及作用机制的见解
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