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用于电子束治疗的黄铜网塞的特性。

Characterization of brass mesh bolus for electron beam therapy.

机构信息

Department of Radiation Oncology, City of Hope, Duarte, CA, 91010, United States of America.

Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, 60637, United States of America.

出版信息

Biomed Phys Eng Express. 2024 Oct 25;10(6). doi: 10.1088/2057-1976/ad87f7.

Abstract

. Bolus is often required for targets close to or on skin surface, however, standard bolus on complex surfaces can result in air gaps that compromise dosimetry. Brass mesh boluses (RPD, Inc., Albertville, MN) are designed to conform to the patient's surface and reduce air gaps. While they have been well characterized for their use with photons, minimal characterization exists in literature for their use with electrons.Dosimetric characteristics of brass mesh bolus was investigated for use with 6, 9 and 12 MeV electrons using a 10 × 10 cmapplicator on standard multi-energy LINAC. Measurements for bolus equivalence and percentage depth doses (PDDs) under brass mesh, as well as surface dose measurements were performed on solid water and a 3D printed resin breast phantom (Anycubic Photon MonoX, Shenzhen, China) using Markusparallel-plate ionization chamber (Model 34045, PTW Freiburg, Germany), thermoluminescent detectors (TLD) and EBRT film. After obtaining surface dose measurements, these were compared to dose calculated on the Pinnacle3 treatment planning system (TPS, 16.2, Koninklijke Philips N.V.).. Measurements of surface dose under brass mesh showed consistently higher dose than without bolus, confirming that brass mesh can increase the PDD at surface up to ∼ 94% of dose at d, depending on incident electron energy. This increase is equivalent to using ∼ 7.2 mm water equivalent bolus for 6 MeV, ∼ 3.6 mm for 9 MeV and ∼ 2.2 mm bolus for 12 MeV electrons. TPS results showed close agreement withmeasurements, confirming the potential for brass mesh as bolus for electron irradiation, provided blousing effect is correctly modelled.. To increase electron surface dose, a brass mesh can be used with equivalent effect of water-density bolus varying with electron energy. Proper implementation could allow for ease of treatment, as well as increase bolus conformality in electron-only plans.

摘要

. 在靠近皮肤表面或在皮肤表面的目标处,通常需要推注,但在复杂表面上使用标准的推注会导致空气间隙,从而影响剂量测量。黄铜网垫(RPD,Inc.,明尼苏达州 Albertville)旨在与患者的表面贴合,减少空气间隙。虽然它们已经在光子治疗中得到了很好的描述,但在电子治疗中,它们的使用特征在文献中很少。本研究使用标准多能 LINAC 的 10×10 cm 敷贴器,对 6、9 和 12 MeV 电子的黄铜网垫剂量学特性进行了研究。在实心水和 3D 打印树脂乳房体模(Anycubic Photon MonoX,深圳,中国)上进行了网垫等效和百分深度剂量(PDD)以及表面剂量测量,使用 Markus 平行板电离室(型号 34045,PTW Freiburg,德国)、热释光探测器(TLD)和 EBRT 胶片。获得表面剂量测量值后,将其与 Pinnacle3 治疗计划系统(TPS,16.2, Koninklijke Philips N.V.)上计算的剂量进行比较。. 在黄铜网下测量的表面剂量始终高于没有使用网垫的剂量,这证实了黄铜网可以将表面的 PDD 增加到 d 处剂量的约 94%,具体取决于入射电子能量。这种增加相当于对于 6 MeV 电子使用约 7.2 mm 水等效的推注,对于 9 MeV 电子使用约 3.6 mm 水等效的推注,对于 12 MeV 电子使用约 2.2 mm 水等效的推注。TPS 结果与测量结果吻合较好,证实了在正确模拟吹风效应的情况下,黄铜网可作为电子照射的推注物。. 为了增加电子表面剂量,可以使用黄铜网,其等效水密度推注效果随电子能量而变化。适当的实施可以使治疗变得更加容易,并且可以提高电子专用计划中的推注贴合度。

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