Vizzari Giampiero, De Ferrari Tommaso, Costa Francesco, Mancini Nastasia, Franzino Marco, Ceresa Fabrizio, Patanè Francesco, Micari Antonio
Interventional Cardiology Unit, 'G. Martino' University Hospital, Via C. Valeria, 1, 98125 Messina, Italy.
Cardio-Thoraco-Vascular Department, Division of Cardiac Surgery, Papardo Hospital, Messina, Italy.
Eur Heart J Case Rep. 2024 Sep 26;8(9):ytae457. doi: 10.1093/ehjcr/ytae457. eCollection 2024 Sep.
The sudden onset of heart failure in high-risk transcatheter aortic valve implantation (TAVI) candidates poses significant challenges, necessitating meticulous planning and consideration of mechanical circulatory support options. Nevertheless, existing data on the efficacy and safety of mechanical circulatory support in this context are limited, along with criteria for patient selection.
An 87-year-old patient, with severe low-flow low-gradient aortic stenosis, presented with acute heart failure and concurrent COVID-19 pneumonia. Despite initial conservative management, her clinical condition deteriorated, requiring inotropic support. The decision was made to perform a rescue TAVI procedure with veno-arterial extracorporeal membrane oxygenation (ECMO) support. The patient underwent successful TAVI while managing complications, including cardiac arrest, with haemodynamic support from veno-arterial ECMO. Post-procedure, the patient showed improved cardiac function and was discharged in stable condition.
This case underscores the significance of strategic patient selection, proactive haemodynamic management, and the judicious use of veno-arterial ECMO in high-risk TAVI, particularly in complex scenarios involving acute heart failure and respiratory insufficiency, exacerbated by COVID-19. It highlights the challenges and critical decision points in TAVI planning, emphasizing the need for further research and standardized guidelines to refine indications for prophylactic mechanical circulatory support in TAVI procedures.
高危经导管主动脉瓣植入术(TAVI)候选患者突然发生心力衰竭带来了重大挑战,需要精心规划并考虑机械循环支持方案。然而,在这种情况下,关于机械循环支持的疗效和安全性的现有数据有限,患者选择标准也有限。
一名87岁患有严重低流量低梯度主动脉瓣狭窄的患者,出现急性心力衰竭并并发新型冠状病毒肺炎。尽管最初采用了保守治疗,但她的临床状况仍恶化,需要使用正性肌力药物支持。决定在静脉-动脉体外膜肺氧合(ECMO)支持下进行挽救性TAVI手术。患者在静脉-动脉ECMO的血流动力学支持下成功接受了TAVI手术,同时处理了包括心脏骤停在内的并发症。术后,患者心脏功能改善,出院时病情稳定。
该病例强调了在高危TAVI中进行策略性患者选择、积极的血流动力学管理以及明智使用静脉-动脉ECMO的重要性,特别是在涉及急性心力衰竭和呼吸功能不全且因新型冠状病毒肺炎而加剧的复杂情况下。它突出了TAVI规划中的挑战和关键决策点,强调需要进一步研究和制定标准化指南,以完善TAVI手术中预防性机械循环支持的适应症。