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Enrichment analysis and chromosomal distribution of gout susceptible loci identified by genome-wide association studies.全基因组关联研究鉴定出的痛风易感位点的富集分析及染色体分布
EXCLI J. 2023 Nov 14;22:1146-1154. doi: 10.17179/excli2023-6481. eCollection 2023.
2
Autoimmune diseases: targets, biology, and drug discovery.自身免疫性疾病:靶点、生物学和药物发现。
Acta Pharmacol Sin. 2024 Apr;45(4):674-685. doi: 10.1038/s41401-023-01207-2. Epub 2023 Dec 14.
3
Janus kinase inhibitors in systemic lupus erythematosus: implications for tyrosine kinase 2 inhibition.系统性红斑狼疮中的Janus激酶抑制剂:酪氨酸激酶2抑制的意义
Front Med (Lausanne). 2023 Jun 29;10:1217147. doi: 10.3389/fmed.2023.1217147. eCollection 2023.
4
Incidence, prevalence, and co-occurrence of autoimmune disorders over time and by age, sex, and socioeconomic status: a population-based cohort study of 22 million individuals in the UK.自身免疫性疾病随时间推移以及按年龄、性别和社会经济状况的发生率、患病率和共病情况:英国 2200 万人的基于人群队列研究。
Lancet. 2023 Jun 3;401(10391):1878-1890. doi: 10.1016/S0140-6736(23)00457-9. Epub 2023 May 5.
5
JAK/STAT pathway: Extracellular signals, diseases, immunity, and therapeutic regimens.JAK/STAT信号通路:细胞外信号、疾病、免疫及治疗方案
Front Bioeng Biotechnol. 2023 Feb 23;11:1110765. doi: 10.3389/fbioe.2023.1110765. eCollection 2023.
6
Mendelian randomization and clinical trial evidence supports TYK2 inhibition as a therapeutic target for autoimmune diseases.孟德尔随机化和临床试验证据支持 TYK2 抑制作为自身免疫性疾病的治疗靶点。
EBioMedicine. 2023 Mar;89:104488. doi: 10.1016/j.ebiom.2023.104488. Epub 2023 Feb 24.
7
Shared etiology of type 1 diabetes and Hashimoto's thyroiditis: a population-based twin study.1 型糖尿病与桥本甲状腺炎的共同病因:基于人群的双胞胎研究。
Eur J Endocrinol. 2022 May 9;186(6):677-685. doi: 10.1530/EJE-22-0025. Print 2022 Jun 1.
8
Association of TYK2 polymorphisms with autoimmune diseases: A comprehensive and updated systematic review with meta-analysis.酪氨酸激酶2(TYK2)基因多态性与自身免疫性疾病的关联:一项综合且更新的荟萃分析系统评价
Genet Mol Biol. 2021 May 3;44(2):e20200425. doi: 10.1590/1678-4685-GMB-2020-0425. eCollection 2021.
9
Studying the Association between STAT4 Gene Polymorphism and Susceptibility to Rheumatoid Arthritis Disease: An Updated Meta-Analysis.研究信号转导和转录激活因子4(STAT4)基因多态性与类风湿性关节炎易感性之间的关联:一项更新的荟萃分析。
Iran J Immunol. 2019 Mar;16(1):71-83. doi: 10.22034/IJI.2019.39408.
10
JAK-STAT Signaling as a Target for Inflammatory and Autoimmune Diseases: Current and Future Prospects.JAK-STAT信号通路作为炎症性和自身免疫性疾病的靶点:现状与未来展望
Drugs. 2017 Apr;77(5):521-546. doi: 10.1007/s40265-017-0701-9.

Autoimmune diseases share a common genetic architecture involving the JAK-STAT pathway.

作者信息

Saadat Iraj, Saadat Mostafa

机构信息

Department of Biology, School of Science, Shiraz University, Shiraz 71467-13565, Iran.

出版信息

EXCLI J. 2024 Aug 27;23:1027-1029. doi: 10.17179/excli2024-7684. eCollection 2024.

DOI:10.17179/excli2024-7684
PMID:39421031
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11483264/
Abstract
摘要