Lahham Elias Edward, Al-Sa'ed Jamal Alddin Bilal Mohammad, Azzam Mosab Mohammed Saleh, Warda Ali Khalid Mahmoud Abu, Al Amleh Hisham
Department of Radiation Oncology, Augusta Victoria Hospital, East Jerusalem, Palestine Territories, 91191, Palestine.
Faculty of Medicine, Palestine Polytechnic University, P.O. Box 198, Hebron, Palestine.
J Surg Case Rep. 2024 Oct 17;2024(10):rjae656. doi: 10.1093/jscr/rjae656. eCollection 2024 Oct.
Colorectal cancer is a prevalent malignancy; it ranks as the third leading cause of cancer-related deaths globally. Despite the effectiveness of surgical intervention for primary tumors, ~30% of patients develop metastases, commonly in the regional lymph nodes, liver, lungs, and peritoneum. Bone metastasis is relatively rare but can occur, typically affecting vertebrae, pelvis, femur, and humerus. This study presents a 68-year-old patient with a history of locally advanced colon cancer who presented with a rapidly enlarging, painful sternal mass. Imaging and biopsy confirmed metastatic colon adenocarcinoma in the sternum. The patient was treated with radiation therapy, resulting in significant symptomatic relief and tumor reduction. This case highlights the rarity of sternal metastasis from colorectal cancer. Given the poor prognosis associated with skeletal metastases in colorectal cancer, this case emphasizes the need for vigilance in monitoring for atypical metastatic sites and the importance of tailored palliative care strategies.
结直肠癌是一种常见的恶性肿瘤;它是全球癌症相关死亡的第三大主要原因。尽管手术干预对原发性肿瘤有效,但约30%的患者会发生转移,常见于区域淋巴结、肝脏、肺和腹膜。骨转移相对少见,但也可能发生,通常影响脊椎、骨盆、股骨和肱骨。本研究报告了一名68岁有局部晚期结肠癌病史的患者,该患者出现了一个迅速增大、疼痛的胸骨肿块。影像学检查和活检证实胸骨有转移性结肠腺癌。该患者接受了放射治疗,症状得到显著缓解,肿瘤缩小。本病例突出了结直肠癌胸骨转移的罕见性。鉴于结直肠癌骨转移预后较差,该病例强调了监测非典型转移部位时保持警惕的必要性以及定制姑息治疗策略的重要性。