Tao Yu-Qi, Zheng Jia-Yi, Xie Zi-Chen, Sun Ke-Yu
Emergency Department, Minhang Hospital, Fudan University, Shanghai, China.
Clin Med Insights Case Rep. 2024 Oct 7;17:11795476241288840. doi: 10.1177/11795476241288840. eCollection 2024.
Diquat poisoning is a fatal condition that is becoming increasingly common. The mortality risk of patients taking lethal doses of diquat is extremely high. It typically leads to rapid dysfunction of multiple organs, including the kidneys, heart, lungs, and brain. Acute kidney injury is usually the first manifestation of this poisoning. However, the optimal treatment strategy for diquat poisoning remains uncertain. Additionally, the mechanism of multiple organ dysfunction syndrome caused by diquat poisoning may resemble the progression of sepsis. In this report, we present 3 cases of diquat poisoning, all of which resulted in death. We emphasize that acute kidney injury is the primary cause of death, and suggest that some strategies used in the treatment of sepsis could be beneficial in managing diquat poisoning-induced acute kidney injury.
敌草快中毒是一种致命疾病,且日益常见。摄入致死剂量敌草快的患者死亡风险极高。它通常会导致包括肾脏、心脏、肺和大脑在内的多个器官迅速功能障碍。急性肾损伤通常是这种中毒的首发表现。然而,敌草快中毒的最佳治疗策略仍不明确。此外,敌草快中毒引起的多器官功能障碍综合征的机制可能类似于脓毒症的进展。在本报告中,我们呈现了3例敌草快中毒病例,均导致死亡。我们强调急性肾损伤是主要死因,并建议一些用于治疗脓毒症的策略可能有助于处理敌草快中毒所致的急性肾损伤。