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敌草快中毒致急性肾损伤引发的思维障碍:病例报告

Thinking Induced by Acute Kidney Injury of Diquat Poisoning: Cases Report.

作者信息

Tao Yu-Qi, Zheng Jia-Yi, Xie Zi-Chen, Sun Ke-Yu

机构信息

Emergency Department, Minhang Hospital, Fudan University, Shanghai, China.

出版信息

Clin Med Insights Case Rep. 2024 Oct 7;17:11795476241288840. doi: 10.1177/11795476241288840. eCollection 2024.

Abstract

Diquat poisoning is a fatal condition that is becoming increasingly common. The mortality risk of patients taking lethal doses of diquat is extremely high. It typically leads to rapid dysfunction of multiple organs, including the kidneys, heart, lungs, and brain. Acute kidney injury is usually the first manifestation of this poisoning. However, the optimal treatment strategy for diquat poisoning remains uncertain. Additionally, the mechanism of multiple organ dysfunction syndrome caused by diquat poisoning may resemble the progression of sepsis. In this report, we present 3 cases of diquat poisoning, all of which resulted in death. We emphasize that acute kidney injury is the primary cause of death, and suggest that some strategies used in the treatment of sepsis could be beneficial in managing diquat poisoning-induced acute kidney injury.

摘要

敌草快中毒是一种致命疾病,且日益常见。摄入致死剂量敌草快的患者死亡风险极高。它通常会导致包括肾脏、心脏、肺和大脑在内的多个器官迅速功能障碍。急性肾损伤通常是这种中毒的首发表现。然而,敌草快中毒的最佳治疗策略仍不明确。此外,敌草快中毒引起的多器官功能障碍综合征的机制可能类似于脓毒症的进展。在本报告中,我们呈现了3例敌草快中毒病例,均导致死亡。我们强调急性肾损伤是主要死因,并建议一些用于治疗脓毒症的策略可能有助于处理敌草快中毒所致的急性肾损伤。

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Thinking Induced by Acute Kidney Injury of Diquat Poisoning: Cases Report.敌草快中毒致急性肾损伤引发的思维障碍:病例报告
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本文引用的文献

4
Programmed Cell Death in Sepsis Associated Acute Kidney Injury.脓毒症相关性急性肾损伤中的程序性细胞死亡
Front Med (Lausanne). 2022 May 17;9:883028. doi: 10.3389/fmed.2022.883028. eCollection 2022.
5
Kidney and lung injury in rats following acute diquat exposure.大鼠急性接触敌草快后的肾和肺损伤
Exp Ther Med. 2022 Apr;23(4):275. doi: 10.3892/etm.2022.11201. Epub 2022 Feb 11.

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