精神疾病的神经科学：面向未来的发展。
The neuroscience of mental illness: Building toward the future.
机构信息
Department of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA; New York State Psychiatric Institute, New York, NY, USA.
Departments of Psychiatry and Behavioral Sciences, Neurology, and Biomedical Engineering, Duke University Medical Center, Durham, NC, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA.
出版信息
Cell. 2024 Oct 17;187(21):5858-5870. doi: 10.1016/j.cell.2024.09.028.
Mental illnesses arise from dysfunction in the brain. Although numerous extraneural factors influence these illnesses, ultimately, it is the science of the brain that will lead to novel therapies. Meanwhile, our understanding of this complex organ is incomplete, leading to the oft-repeated trope that neuroscience has yet to make significant contributions to the care of individuals with mental illnesses. This review seeks to counter this narrative, using specific examples of how neuroscientific advances have contributed to progress in mental health care in the past and how current achievements set the stage for further progress in the future.
精神疾病源于大脑功能障碍。尽管许多神经外因素会影响这些疾病，但最终，正是大脑科学将为新疗法的出现提供线索。与此同时，我们对这个复杂器官的认识并不完整，这导致了一个经常被重复的比喻，即神经科学尚未为精神疾病患者的护理做出重大贡献。本文旨在反驳这一观点，通过具体例子说明神经科学的进展在过去是如何促进精神卫生保健的，并展示当前的成就为未来的进一步发展奠定了基础。
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