TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, No.37, Twelve Bridges Road, Jinniu District, Chengdu City, Sichuan Province, 610075, China.
Chengdu Fifth People's Hospital, The Second Clinical Medical College, Affiliated Fifth People's Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610041, China.
BMC Urol. 2024 Oct 18;24(1):228. doi: 10.1186/s12894-024-01626-1.
Polyorchidism is an uncommon congenital condition often discovered incidentally, which may significantly impact male fertility. We present a case of a 34-year-old man with unilateral polyorchidism and associated severe asthenozoospermia and teratozoospermia. Despite normal hormonal levels and no detected genetic anomalies, the patient's sperm showed mitochondrial damage, and his fertility remained compromised after conservative management and assisted reproductive attempts. This case underscores the intricate relationship between polyorchidism and male infertility, highlighting the need for personalized management strategies and further research into its etiology and impact.
多睾症是一种罕见的先天性疾病，通常是偶然发现的，可能会对男性生育能力产生重大影响。我们报告了一例 34 岁男性单侧多睾症伴严重弱精症和畸形精子症。尽管激素水平正常且未检测到遗传异常，但患者的精子显示线粒体损伤，并且在保守治疗和辅助生殖尝试后，其生育能力仍然受损。该病例强调了多睾症与男性不育之间的复杂关系，突出了需要制定个性化的管理策略，并进一步研究其病因和影响。
