Gaur Dushyant Singh, Talekar Manju S, Pathak Ved Prakash
Department of Pathology, Himalayan Institute of Medical Sciences, Jolly Grant, Dehradun 248 140, Uttarakhand, India.
Indian J Pathol Microbiol. 2010 Jan-Mar;53(1):35-40. doi: 10.4103/0377-4929.59180.
Lifestyle factors, like alcohol intake and cigarette smoking, have been reported to affect male fertility.
To find out the specific impact of alcohol and smoking on semen quality of male partners of couples seeking treatment for primary infertility.
From the semen samples analyzed in our andrology laboratory, results of 100 alcoholics and 100 cigarette smoker males were studied following WHO guidelines and compared with 100 strict nonalcoholic and nonsmoker males for presence of asthenozoospermia, oligozoospermia and teratozoospermia.
Data was analyzed by F- test using Microsoft Office Excel 2003.
Only 12% alcoholics and six per cent smokers showed normozoospermia compared to 37 % nonalcoholic nonsmoker males. Teratozoospermia, followed by oligozoospermia dominated alcoholics. Overall impact of asthenozoospermia and teratozoospermia, but not of oligozoospermia, was observed in smokers. Light smokers predominantly showed asthenozoospermia. Heavy alcoholics and smokers showed asthenozoospermia, teratozoospermia as well as oligozoospermia.
Asthenozoospermia, the most common semen variable in our study, can be an early indicator of reduction in quality of semen. Alcohol abuse apparently targets sperm morphology and sperm production. Smoke-induced toxins primarily hamper sperm motility and seminal fluid quality. Progressive deterioration in semen quality is related to increasing quantity of alcohol intake and cigarettes smoked.
据报道，生活方式因素，如饮酒和吸烟，会影响男性生育能力。
了解饮酒和吸烟对寻求原发性不孕症治疗的夫妇中男性伴侣精液质量的具体影响。
根据世界卫生组织指南，对我们男科实验室分析的精液样本中100名酗酒男性和100名吸烟男性的结果进行研究，并与100名严格不饮酒和不吸烟的男性进行比较，以检测是否存在弱精子症、少精子症和畸形精子症。
使用Microsoft Office Excel 2003通过F检验对数据进行分析。
只有12%的酗酒者和6%的吸烟者精液正常，而不饮酒不吸烟的男性这一比例为37%。畸形精子症在酗酒者中占主导地位，其次是少精子症。在吸烟者中观察到弱精子症和畸形精子症的总体影响，但少精子症没有。轻度吸烟者主要表现为弱精子症。重度酗酒者和吸烟者表现出弱精子症、畸形精子症以及少精子症。
弱精子症是我们研究中最常见的精液变量，可能是精液质量下降的早期指标。酗酒显然会影响精子形态和精子生成。吸烟产生的毒素主要会妨碍精子活力和精液质量。精液质量的逐渐恶化与饮酒量和吸烟量的增加有关。
