Knecht H, Rhyner K, Streuli R A
Br J Haematol. 1986 Jan;62(1):65-73. doi: 10.1111/j.1365-2141.1986.tb02901.x.
Toxoplasma serology was performed in 28 patients with hairy-cell leukaemia and was positive in eight patients (29%). In two patients (7%) reactivated toxoplasmosis was proven by either isolation of Toxoplasma gondii or by significant antibody titre rise with generation of specific IgM-antibodies. In four patients (14%), a clinical diagnosis of active toxoplasmosis was based on signs and symptoms, serologic tests, and response to specific treatment. The high proportion of patients in which active toxoplasmosis was proven or probable (six; 21%) may be related to the presence of severe monocytopenia. In patients with hairy-cell leukaemia developing fever of unknown origin and myositis, toxoplasma serology should be performed, particularly because treatment of active toxoplasmosis usually is successful.
对28例毛细胞白血病患者进行了弓形虫血清学检测，其中8例（29%）呈阳性。2例（7%）患者经弓形虫分离或特异性IgM抗体产生导致抗体滴度显著升高，证实为弓形虫病复发。4例（14%）患者根据体征和症状、血清学检查及对特异性治疗的反应，临床诊断为活动性弓形虫病。已证实或可能患有活动性弓形虫病的患者比例较高（6例；21%），这可能与严重单核细胞减少症的存在有关。对于出现不明原因发热和肌炎的毛细胞白血病患者，应进行弓形虫血清学检测，特别是因为活动性弓形虫病的治疗通常是成功的。
