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[酒精性病因所致各种肝脏疾病中脂质过氧化的终产物]

[Final products of lipid peroxidation in various liver diseases of alcoholic etiology].

作者信息

Loginov A S, Dzhalalov K D, Erin A N, Prilipko L L

出版信息

Biull Eksp Biol Med. 1986 Jan;101(1):26-8.

PMID:3942811
Abstract

The content of lipid peroxidation products in the plasma of patients with various forms of alcohol-induced liver disorders was investigated. Plasma levels of lipid hydroperoxides in this group of patients were found to be the same as in healthy controls. Plasma content of fluorescent products of lipid oxidation was significantly elevated in patients suffering from acute alcoholic hepatitis and active alcoholic liver cirrhosis, and especially in patients with edematoascitic syndrome. The dynamics of fluorescent product plasma level reduction significantly correlated with the improvement of clinical status in the treatment of abstinent patients.

摘要

对患有各种形式酒精性肝病患者血浆中脂质过氧化产物的含量进行了研究。发现该组患者血浆中的氢过氧化物水平与健康对照组相同。脂质氧化荧光产物的血浆含量在急性酒精性肝炎和活动性酒精性肝硬化患者中显著升高,尤其是在伴有水肿腹水综合征的患者中。在戒酒患者的治疗中,荧光产物血浆水平降低的动态变化与临床状况的改善显著相关。

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